1-Isopropylpiperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4318-42-7 |
| Product name | 1-Isopropylpiperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Isopropylpiperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Isopropylpiperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Isopropylpiperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key structural building block for synthesizing antipsychotics (e.g., blonanserin), antidepressants, and 5-HT receptor modulators | Used as an N-substituted piperazine derivative in nucleophilic substitution, acylation, or alkylation reactions to construct the core scaffold of target molecules |
| Pesticide Development | Structural modification component for novel insecticides and plant growth regulators | Applied to introduce the isopropylpiperazine group, enhancing selective binding affinity toward target enzymes (e.g., acetylcholinesterase) |
| Materials Science | Functionalized monomer for high-performance polymers (e.g., polyamides, polyureas) | Employed in condensation polymerization with diacids or diisocyanates to impart pH responsiveness, metal ion chelation capability, or improved solubility |
| Organic Synthesis Reagents | Building block for chiral catalyst ligands (following chiral derivatization) | Processed via N-protection, introduction of chiral centers (e.g., asymmetric alkylation), and deprotection to prepare C2-symmetric bis-piperazine ligand precursors |
Manufacturing Quality Control of 1-Isopropylpiperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 1-isopropylpiperazine peak area against a calibration curve using an internal or external standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on iodine consumption in a pyridine-methanol solvent system. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by weighing residue after high-temperature ashing at 700-800 C. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies total heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion by measuring atomic absorption at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Identifies and quantifies structurally related impurities using reversed-phase separation and UV absorbance at 210-230 nm. |
| Acid Value | Acid-Base Titration | Determines free acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Specific Optical Rotation | Polarimetry | Measures the angle of rotation of plane-polarized light caused by chiral molecules in solution at specified concentration and path length. |
| Density | Digital Density Meter | Determines mass per unit volume at 20 C using oscillating U-tube principle based on frequency change. |
| Refractive Index | Refractometry | Measures bending of light at air-sample interface using Abbe refractometer or digital equivalent at 20 C. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a 10% w/w aqueous solution using calibrated glass electrode and reference electrode. |
| Volatile Impurities | Headspace Gas Chromatography (HS-GC) | Detects low-boiling residual solvents (e.g., acetone, methanol) by analyzing vapor phase above sample at controlled temperature. |
Technical Specifications of 1-Isopropylpiperazine
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.480–1.490 |
| Relative Density (20°C/25°C) | 0.865–0.875 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Isopropylpiperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Isopropylpiperazine
Packaging of 1-Isopropylpiperazine
Industrial 1-Isopropylpiperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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