6-Chloro-3-methyluracil Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4318-56-3 |
| Product name | 6-Chloro-3-methyluracil |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Chloro-3-methyluracil
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Chloro-3-methyluracil Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Chloro-3-methyluracil
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antitumor agents (e.g., 5-fluorouracil) | Used in organic synthesis and catalytic reactions |
| Agrochemicals | Intermediate for herbicide production (e.g., bromoxynil) | Applied in halogenation and condensation reactions |
| Dyes | Precursor for heterocyclic dye synthesis | Employed in coupling and oxidation reactions |
| Research | Structural modification of pyrimidine compounds in chemical research | Used in laboratory-scale synthesis |
Manufacturing Quality Control of 6-Chloro-3-methyluracil
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | A C18 reversed-phase column is used, with methanol/water or acetonitrile/water (containing a small amount of acid such as phosphoric acid or formic acid) as the mobile phase. Detection is performed using a UV detector (wavelength 240–270 nm), with external or internal standard method for quantitation. Suitable for purity evaluation of the main component. |
| Structural Confirmation | Infrared Spectroscopy (IR) | Identifies molecular skeleton and substituents through characteristic functional group absorption peaks (e.g., C=O stretching ~1700 cm⁻¹, C-Cl stretching ~750 cm⁻¹, N-H bending ~1600 cm⁻¹), and compares with reference spectra. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H-NMR / ¹³C-NMR) | Measured in DMSO-d₆ or CDCl₃. ¹H-NMR identifies methyl singlets (~δ 2.5 ppm) and aromatic proton signals (~δ 7.8–8.2 ppm). ¹³C-NMR confirms carbon skeleton and chlorine substitution positions, used for structural verification. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Performs gradient or isocratic elution to detect possible impurities such as unreacted starting materials (uracil derivatives), dechlorinated products, and oxidation by-products. Impurity content is calculated based on impurity peak area (typically ≤0.5%). |
| Chlorine Content Determination | Ion Chromatography (IC) or Oxygen Flask Combustion + Ion Selective Electrode | After alkaline hydrolysis or oxygen flask combustion, chloride ions are released. Cl⁻ concentration is detected by ion chromatography or quantified using a chloride ion-selective electrode to verify whether the chlorine content matches the theoretical value (theoretical Cl% ≈ 24.5%). |
| Melting Point Determination | Capillary Melting Point Apparatus | Measures the melting point range of the pure substance (literature value approximately 195–200°C), used for preliminary purity assessment; a wide melting range indicates the presence of impurities. |
| Moisture Determination | Karl Fischer Titration | Suitable for trace moisture detection (≤0.5%) to ensure sample dryness and prevent hydrolysis or stability issues. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Measures maximum absorption wavelength (λmax ≈ 250–260 nm) in ethanol or aqueous solution, used for establishing quantitative methods or rapid screening. |
| Heavy Metal Residue Testing | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residues of lead, cadmium, mercury, arsenic, etc., according to pharmacopoeia standards (e.g., USP/EP), ensuring compliance with pharmaceutical-grade requirements (typically ≤10 ppm). |
| Crystal Form Analysis (Optional) | X-Ray Powder Diffraction (XRPD) | If the substance is a solid active pharmaceutical ingredient, this method confirms crystalline form to avoid differences in solubility and stability due to polymorphism. |
Technical Specifications of 6-Chloro-3-methyluracil
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Chloro-3-methyluracil
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Chloro-3-methyluracil
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Industrial 6-Chloro-3-methyluracil Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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