China Factory Direct
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| CAS number | 436-72-6 |
| Product name | 5-FLUORO-4-HYDROXYQUINAZOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key structural motif for synthesizing antimalarial agents (e.g., quinoline derivatives) and anticancer candidate compounds | Used as a starting material in multistep organic synthesis; target molecular frameworks are constructed via halogenation, amination, coupling, and related reactions |
| Pesticide Development | Lead compound for designing novel fluorinated quinoline-based fungicides and insecticides | Fluorine atoms are introduced during molecular design to enhance lipophilicity and target binding affinity; structural modifications are followed by biological activity screening |
| Materials Science | Functionalized precursor for fluorescent probes and organic optoelectronic materials | Derivatized via O-alkylation or N-acylation to tune photophysical properties for sensor or OLED device development |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at characteristic wavelength, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Separates and quantifies impurities by retention time and UV response relative to reference standards or area normalization. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents using gas chromatography with flame ionization detection against calibration curves. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration based on iodine consumption in pyridine-methanol buffer. |
| Heavy Metals | ICP-OES | Determines total elemental metals (e.g., Pb, Cd, Hg, As) by plasma excitation and atomic emission intensity measurement. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after high-temperature combustion of sample with sulfuric acid pretreatment. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of crystalline solid against defined standards under controlled lighting. |
| Loss on Drying | Thermogravimetric Analysis | Measures mass loss upon heating under specified conditions to determine volatile content including moisture and solvents. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water) using calibrated electrode. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after ignition at 700-800 C without sulfuric acid treatment. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152 °C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.