China Factory Direct
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| CAS number | 4378-13-6 |
| Product name | H-THR(TBU)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug synthesis intermediate for antiviral agents (e.g., HIV protease inhibitors) and antibiotics | Used as a chiral auxiliary or building block in multistep organic synthesis; incorporated into target molecules via reactions such as esterification, amidation, and deprotection |
| Biochemical Research | Site-specific incorporation of non-canonical amino acids in protein engineering and enzymology studies | Site-specifically incorporated into recombinant proteins in cellular or cell-free expression systems using genetic code expansion technology |
| Pesticide Development | Chiral intermediate for structural optimization of novel insecticides and plant growth regulators | Introduced as a chiral side chain onto heterocyclic core structures; active molecular scaffolds constructed via catalytic hydrogenation, hydrolysis, and related steps |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC with UV detection | Quantitative determination using reversed-phase HPLC and UV absorbance at 200-220 nm relative to a certified reference standard. |
| Specific Optical Rotation | [alpha]D measurement | Measurement of optical rotation at 20-25 C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Chiral Purity | Chiral HPLC | Separation and quantification of enantiomers on a chiral stationary phase, detecting L-isomer excess versus racemate or D-isomer impurity. |
| Water Content | Karl Fischer titration | Volumetric or coulometric titration based on iodine-sulfur dioxide reaction stoichiometry to determine trace water content. |
| Residue on Ignition | Gravimetric analysis after ignition | Heating sample at 700-800 C to oxidize organic matter; residue weight reflects inorganic ash content. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma emission spectroscopy. |
| Chloride Content | Ion chromatography | Separation and conductivity detection of chloride ions following aqueous extraction and filtration. |
| Sulfate Content | Ion chromatography | Quantification of sulfate ions via anion exchange separation and suppressed conductivity detection. |
| Related Substances | HPLC with gradient elution | Detection and quantification of structurally similar impurities (e.g., degradants, synthesis intermediates) using optimized reverse-phase conditions. |
| pH of Aqueous Solution | Potentiometric pH measurement | Determination of pH in a defined aqueous suspension (e.g., 1% w/v) using calibrated glass electrode. |
| Particle Size Distribution | Laser diffraction | Analysis of dry or wet dispersed sample to obtain volumetric particle size distribution based on light scattering patterns. |
| Microbial Limits | Membrane filtration followed by plate count | Enumeration of aerobic mesophilic bacteria and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 230-235°C (decomposes) |
| Optical Rotation | -46.0 to -42.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.