China Factory Direct
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| CAS number | 438056-69-0 |
| Product name | 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an organic synthesis intermediate for synthesizing biologically active compounds (e.g., kinase inhibitors, anticancer or anti-inflammatory drug candidates) | Integrated into multi-step organic syntheses via amidation, reduction, or coupling reactions to construct target molecular scaffolds |
| Chemical Research | Applied in constructing morpholinone-containing heterocyclic compound libraries to support drug screening and structure–activity relationship (SAR) studies | Structural modifications performed using solid-phase or solution-phase synthesis, combined with protection/deprotection strategies |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical form (e.g., white to off-white crystalline powder), and presence of foreign matter or caking. |
| Purity (Assay) | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with UV detection (e.g., at 254 nm); quantify active ingredient using external standard or area normalization method. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Employ gradient elution to separate potential process impurities and degradation products; perform qualitative and quantitative analysis based on relative retention times and peak areas. |
| Water Content | Karl Fischer Titration | Determine water content by coulometric or volumetric titration to ensure compliance with standards for loss on drying or moisture content. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with capillary column and FID detector; control residual solvents according to ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Apparatus | Measure the temperature range from initial melting to complete melting for identification and assessment of crystalline purity. |
| pH (Solution) | pH Meter Measurement | Prepare an aqueous solution of specified concentration and measure acidity/basicity using a calibrated pH meter to assess acidic or basic impurities. |
| Heavy Metals | ICP-MS or Atomic Absorption Spectroscopy | After sample digestion, detect elemental residues such as lead, cadmium, mercury, and arsenic; comply with ICH Q3D limits for elemental impurities. |
| Loss on Drying | Weight Loss upon Drying | Dry the sample at a specified temperature (e.g., 105°C) to constant weight; calculate percentage weight loss to evaluate volatile content. |
| Specific Optical Rotation (if applicable) | Polarimeter Measurement | For chiral molecules or when optical activity is relevant, measure optical rotation at a specific wavelength to assess optical purity. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | Confirm molecular structure using ¹H-NMR, ¹³C-NMR, and high-resolution mass spectrometry (HRMS); used for release testing or during development phase. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=99.0%(HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 182-186°C |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.