5-Fluoroisatin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 443-69-6 |
| Product name | 5-Fluoroisatin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Fluoroisatin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Fluoroisatin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Fluoroisatin
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used to synthesize biologically active fluorinated compounds, such as kinase inhibitors and anticancer drug candidates |
| Organic synthesis | Preparation of fluorinated isatin derivatives | Serves as a starting material for constructing fluorinated heterocyclic structures, participating in condensation, cyclization, and related reactions |
| Materials science | Functional dye research | Applied in structural modification for developing novel fluorescent probes or optical functional materials |
Manufacturing Quality Control of 5-Fluoroisatin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on UV absorbance of 5-fluoroisatin at characteristic wavelength, using external standard calibration. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection against certified reference standards. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification via inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on stoichiometric reaction of iodine with water in anhydrous methanol/pyridine medium. |
| Related Substances (Impurities) | HPLC-UV/DAD | Identification and quantification of structurally related impurities (e.g., isatin, 5-chloroindole, des-fluoro byproducts) using gradient HPLC with diode array detection and reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic residue after high-temperature ashing (700–800 °C) followed by precise weighing of residual sulfate ash. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection against chloride calibration standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular dependence of laser light scattering intensity from a dispersed sample in liquid or air. |
| Specific Optical Rotation | [α]D Measurement (Polarimetry) | Determination of chiral purity (if applicable) or identity confirmation by measuring the angle of rotation of plane-polarized light at 589 nm. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a defined aqueous suspension (e.g., 1% w/v in water) using calibrated glass electrode and pH meter. |
| Bulk and Tapped Density | ASTM D6393 (Powder Rheology) | Determination of powder flow properties via volumetric measurement before and after standardized mechanical tapping under controlled conditions. |
| Microbial Limits | Membrane Filtration + Culture Enumeration | Quantitative assessment of aerobic microbial count and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial methods (USP <61>/<62>). |
Technical Specifications of 5-Fluoroisatin
| Test Item | Specification |
|---|---|
| Appearance | Red solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 225-229°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Fluoroisatin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Fluoroisatin
Packaging of 5-Fluoroisatin
Industrial 5-Fluoroisatin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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