2-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 444120-94-9 |
| Product name | 2-CHLORO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 444120-94-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 444120-94-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 444120-94-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for anticancer agents (e.g., alectinib, brigatinib) | Constructing carbon–carbon bonds via Suzuki–Miyaura coupling |
| Pharmaceuticals | Synthetic building block for antiviral agents | Constructing complex pyridine-derived scaffolds |
| Organic Synthesis | Boronic ester reagent for aryl–aryl coupling reactions | Palladium-catalyzed cross-coupling reactions |
| Chemical R&D | Drug synthesis and structural modification | Serving as an electrophilic reagent for introducing pyridine rings |
Manufacturing Quality Control of 444120-94-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by comparing retention times and peak areas to qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection against calibration curves. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in a controlled electrochemical or chemical system. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Hg, As) by atomizing the sample and detecting elemental ions via mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection relative to chloride standard solutions. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C and weighing residual non-volatile matter after cooling. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of bulk material against defined standards under controlled lighting conditions. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension or dry state by analyzing angular scattering pattern of laser light. |
| Bulk Density | Tap Density Tester | Determines mass per unit volume of powder in a standardized graduated cylinder after mechanical tapping per USP <616>. |
| Specific Optical Rotation | Polarimetry | Measures angle of rotation of plane-polarized light caused by chiral centers in solution using sodium D-line light source. |
Technical Specifications of 444120-94-9
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89 °C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 444120-94-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 444120-94-9
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Industrial 444120-94-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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