China Factory Direct
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| CAS number | 444666-39-1 |
| Product name | 2-Chloro-5-fluorobenzeneboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Pharmaceutical Intermediates | Used to synthesize organic boronic acid derivatives for antitumor and antiviral drugs |
| Agrochemicals | Agrochemical Intermediates | Applied as a key intermediate in the synthesis of fluorinated phenyl insecticides or herbicides |
| Materials Science | Liquid Crystal Materials | Used to prepare fluorinated phenyl compounds for high-performance liquid crystal display materials |
| Organic Synthesis | Coupling Reaction Reagent | Applied as an arylboronic acid reagent in Suzuki coupling reactions |
| R&D | New Compound Synthesis | Used in research to construct novel functional molecules containing fluorinated phenylboronic acid structures |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., isomers, residual starting materials, dehalogenated by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., THF, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Measures trace levels of toxic elements (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Ion | Ion Chromatography | Quantifies chloride impurity using suppressed conductivity detection after separation on anion-exchange column. |
| Residual Palladium | ICP-OES | Determines palladium residue from cross-coupling catalysts by microwave-assisted acid digestion followed by inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against established reference standard. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 105 C for 2 hours under vacuum. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a 1% w/v suspension in water using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry powder mode using Mie theory-based laser scattering principle. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.