China Factory Direct
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| CAS number | 445-04-5 |
| Product name | 4-AMINO-3-(TRIFLUOROMETHYL)PHENOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Serves as a key structural unit in the synthesis of trifluoromethyl-containing active pharmaceutical ingredients (APIs), such as the diuretic etodolac and its derivatives. |
| Agrochemicals | Agrochemical Intermediates | Used in the synthesis of herbicides, insecticides, or fungicides containing a trifluoromethylphenyl ether structure. |
| Dyes & Pigments | Dye Intermediates | Employed in the synthesis of lightfast and washfast dark disperse dyes and acid dyes; the trifluoromethyl group enables shade adjustment. |
| Materials Science | Functional Monomer | Acts as a functional monomer in the synthesis of specialty polymers or liquid crystal materials, where incorporation of the trifluoromethyl group enhances thermal stability or solubility. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 275 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; water reacts stoichiometrically with iodine and sulfur dioxide in methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion; detection based on mass-to-charge ratio and isotopic abundance. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anion on an anion-exchange column with suppressed conductivity detection; quantified against sodium chloride calibration curve. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using controlled heating rate and visual observation of meniscus movement in capillary tube. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light against specified reference (white crystalline powder). |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to determine inorganic ash content. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined saturated aqueous suspension (e.g., 10 mg/mL) using calibrated pH electrode. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after controlled tapping of sample in calibrated cylinder per USP <616>. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity as function of angle to calculate volume-based particle size distribution in dispersed slurry. |
| Test Item | Specification |
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| Appearance | Black solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 112–116°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.