4-Fluoro-2-nitroanisole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 445-83-0 |
| Product name | 4-Fluoro-2-nitroanisole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Fluoro-2-nitroanisole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Fluoro-2-nitroanisole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Fluoro-2-nitroanisole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of the antidepressant venlafaxine | Prepared via multi-step organic synthesis—including reduction and substitution—to yield the active pharmaceutical ingredient |
| Pesticides | Intermediate in the synthesis of certain fluorinated aromatic herbicides or insecticides | Introduced into target molecular structures via nucleophilic substitution or coupling reactions |
| Dyes & Pigments | Fluorinated aromatic compound used as a precursor in specialty dye synthesis | Participates in dye synthesis processes such as diazotization and coupling |
| Organic Synthesis | General-purpose intermediate for constructing fluorinated benzene ring systems | Derivatized through nitro group reduction, methoxy group transformation, or fluorine-directed metal-catalyzed reactions |
Manufacturing Quality Control of 4-Fluoro-2-nitroanisole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., methanol, toluene) using capillary GC with flame ionization detection and external calibration. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element trace metal quantification after acid digestion, based on isotopic mass spectrometry with ultra-low detection limits. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min). |
| Appearance & Color | Visual Inspection / Hazen Color Scale | Subjective assessment of physical state and color intensity compared to platinum-cobalt standards. |
| Residue on Ignition | Gravimetric Analysis | Mass determination of non-volatile inorganic residue after high-temperature ashing (700–800 °C) and cooling in desiccator. |
| Related Substances (Impurity Profile) | HPLC-DAD | Identification and quantification of structurally related impurities (e.g., isomers, nitro-reduction products) using diode array detection and retention time matching. |
| pH of Aqueous Suspension | pH Meter Measurement | Determination of acidity/basicity of a saturated aqueous suspension (e.g., 1% w/v) using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity (though compound is achiral, used for consistency verification). |
Technical Specifications of 4-Fluoro-2-nitroanisole
| Test Item | Specification |
|---|---|
| Appearance | Light orange to yellow to green crystalline powder |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Fluoro-2-nitroanisole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Fluoro-2-nitroanisole
Packaging of 4-Fluoro-2-nitroanisole
Industrial 4-Fluoro-2-nitroanisole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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