3-Methoxypyridine-5-boronic acid pinacol ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 445264-60-8 |
| Product name | 3-Methoxypyridine-5-boronic acid pinacol ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Methoxypyridine-5-boronic acid pinacol ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Methoxypyridine-5-boronic acid pinacol ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Methoxypyridine-5-boronic acid pinacol ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in the synthesis of anticancer agents (e.g., EGFR inhibitors) | Suzuki-Miyaura cross-coupling reaction |
| Agrochemicals | Applied to construct molecular scaffolds of novel pyrimidine-containing insecticides and fungicides | Palladium-catalyzed cross-coupling for C–C bond formation |
| Materials Science | Employed as a structural building block for organic optoelectronic materials (e.g., dopants in OLED emissive layers) | Directed coupling and polymerization reactions involving boronate esters |
Manufacturing Quality Control of 3-Methoxypyridine-5-boronic acid pinacol ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-230 nm based on peak area response against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., des-methoxy, hydrolyzed, or dimeric analogs) using gradient HPLC-UV with relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) by headspace GC with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration where iodine is generated electrochemically or added reagent-wise to react stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Cu) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution or external calibration. |
| Residual Boron | ICP-OES | Measures total boron content after microwave-assisted nitric/hydrochloric acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of particulates or foreign matter against established reference standards under controlled lighting. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under specified vacuum/temperature conditions to determine volatile and moisture content. |
| Specific Optical Rotation | Polarimetry | Measures angle of rotation of plane-polarized light in solution to confirm chiral integrity and enantiomeric consistency. |
| Residual Palladium | ICP-MS | Quantifies palladium catalyst residue using isotope-specific detection after closed-vessel microwave digestion and matrix-matched calibration. |
Technical Specifications of 3-Methoxypyridine-5-boronic acid pinacol ester
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 118–122°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Methoxypyridine-5-boronic acid pinacol ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Methoxypyridine-5-boronic acid pinacol ester
Safety Information of 3-Methoxypyridine-5-boronic acid pinacol ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Methoxypyridine-5-boronic acid pinacol ester
Industrial 3-Methoxypyridine-5-boronic acid pinacol ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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