4,6-Dichloro-2-(methylsulfonyl)pyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4489-34-3 |
| Product name | 4,6-Dichloro-2-(methylsulfonyl)pyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-Dichloro-2-(methylsulfonyl)pyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing sulfonylurea herbicides (e.g., chlorimuron-ethyl, nicosulfuron) | Condensed with aromatic amines or heterocyclic amines via nucleophilic substitution to form the sulfonylurea bridge |
| Pharmaceuticals | Used to synthesize biologically active pyrimidine derivatives, such as antiviral or anticancer drug candidates | Serves as a building block in multistep organic synthesis to introduce both the methanesulfonyl and chloropyrimidine structural motifs |
| Fine Chemicals | Intermediate for preparing other functionalized pyrimidine compounds | Undergoes selective chlorine substitution or methanesulfonyl group transformation under basic conditions |
Manufacturing Quality Control of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; relative retention times and UV spectra support structural assignment. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, dichloromethane) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion; detection based on characteristic atomic emission wavelengths following plasma excitation. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| Sulfate Residue | Gravimetric Analysis | Precipitation as barium sulfate under controlled conditions, followed by filtration, drying, and weighing of the precipitate. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually through capillary tube under controlled heating rate. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate size distribution based on Mie theory assumptions. |
| Bulk Density | USP <616> Tap Density Method | Measurement of mass per unit volume before and after standardized mechanical tapping to assess powder flow and packing behavior. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Weight loss measured upon heating under nitrogen or air to determine volatile and moisture content up to 105 C. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode system. |
Technical Specifications of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (GC-MS) |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
Safety Information of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4,6-Dichloro-2-(methylsulfonyl)pyrimidine
Industrial 4,6-Dichloro-2-(methylsulfonyl)pyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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