7-Hydroxygranisetron Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4498-67-3 |
| Product name | 7-Hydroxygranisetron |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-Hydroxygranisetron
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-Hydroxygranisetron Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-Hydroxygranisetron
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor agents (e.g., key intermediate for the Bcl-2 inhibitor ABT-199/Venetoclax) | Multi-step organic synthesis, including palladium-catalyzed coupling, amidation, and cyclization |
| Pharmaceuticals | Construction of heterocyclic scaffolds for kinase inhibitors and G protein-coupled receptor (GPCR)-targeted compounds | Used as a nitrogen-containing fused-ring building block in Suzuki, Heck, and other cross-coupling reactions, followed by functional group transformations |
| Agrochemicals | Bioactive heterocyclic fragment in molecular design of novel insecticides and fungicides | Introduction of indazole carboxylic acid structure to enhance target binding affinity and metabolic stability; commonly modified via esterification or amidation for structure–activity relationship studies |
| Materials Science | Structural unit in organic optoelectronic functional materials (e.g., hole-transport layers for OLEDs) | Carboxyl-group anchoring to metal oxide interfacial layers, or decarboxylative coupling to synthesize conjugated indazole derivatives |
Manufacturing Quality Control of 7-Hydroxygranisetron
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water via reaction with iodine, sulfur dioxide, and base in methanol/pyridine medium. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after eluent gradient separation. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue mass after high-temperature incineration of sample in sulfuric acid medium followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range at which solid-to-liquid phase change occurs under controlled heating. |
| Appearance | Visual Inspection | Assessment of physical state, color, and absence of visible particulates or discoloration against established reference standards. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution in a dispersed slurry. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized mechanical tapping of a powder sample in a graduated cylinder. |
Technical Specifications of 7-Hydroxygranisetron
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-Hydroxygranisetron
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-Hydroxygranisetron
Packaging of 7-Hydroxygranisetron
Industrial 7-Hydroxygranisetron Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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