1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4498-68-4 |
| Product name | 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antitumor agents (e.g., PARP inhibitors) | Cyclized with hydrazine derivatives to prepare indazole-based active molecules, followed by hydrolysis and amidation to construct targeted drug structures |
| Pesticide R&D | Structural modification unit for novel fungicides and insecticides | Introduced as a heterocyclic scaffold into pesticide molecules to enhance selective inhibitory activity against pathogens or pests |
| Organic Synthesis | Multifunctional heterocyclic building block for constructing nitrogen-containing fused-ring compounds | After ester hydrolysis to carboxylic acid, participates in coupling reactions (e.g., Suzuki, Heck) or undergoes derivatization via reduction, substitution, and other functional group transformations |
Manufacturing Quality Control of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by separation on C18 column with gradient elution and UV detection. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., ethanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine generation in pyridine-methanol medium. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (Pb, Cd, Hg, As) after acid digestion via inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after ignition at 700-750 C following sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particles or discoloration against white background under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral centers in solution at specified concentration and wavelength. |
| pH of Aqueous Suspension | pH Meter | Determines acidity/basicity of a saturated aqueous suspension using calibrated glass electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighs non-volatile residue remaining after heating sample to 600-650 C in platinum crucible. |
Technical Specifications of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
Safety Information of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
Industrial 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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