China Factory Direct
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| CAS number | 450-89-5 |
| Product name | 2-CHLORO-5-FLUOROANISOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of fungicides such as fludioxonil | Prepared via multi-step reactions including nitration, reduction, diazotization, fluorination, and methylation to produce fludioxonil |
| Pharmaceuticals | Structural building block for fluorinated aryl ether-based drugs, including anti-inflammatory and antitumor agents | Serves as a fluorinated aryloxy methyl moiety in coupling reactions (e.g., Suzuki, Ullmann) to construct active pharmaceutical ingredients |
| Materials | Intermediate for liquid crystal monomers and organic electroluminescent (OLED) materials | Introduced into liquid crystal core structures or hole-transport layer molecules via halogen exchange, boronic esterification, or direct coupling |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a calibrated column and carrier gas. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Separation followed by mass spectral identification and semi-quantitative assessment of impurities relative to the main peak. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvent residues are vaporized in sealed vials and quantified via GC-FID using calibrated external standards. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of anions on an ion-exchange column followed by conductivity detection and quantification against chloride standard. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Sample digested in acid matrix, then atomized/ionized in plasma; elemental quantification based on isotope-specific mass detection. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution with potentiometric or indicator endpoint detection. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement at 455 nm | Comparison of sample solution color intensity against platinum-cobalt standard solutions or absorbance measurement at specified wavelength. |
| Density at 20 C | Digital Density Meter (Oscillating U-tube) | Measurement of sample density based on resonant frequency shift of a vibrating U-shaped tube filled with the liquid. |
| Refractive Index at 20 C | Digital Refractometer | Determination of refractive index via critical angle measurement of light passing through the sample at controlled temperature. |
| Non-Volatile Residue | Gravimetric Analysis (Evaporation and Weighing) | Sample evaporated to dryness under controlled conditions; residue weighed after cooling in desiccator. |
| Odor | Sensory Evaluation by Trained Panel | Organoleptic assessment against reference material to detect off-odor indicative of degradation or contamination. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.21–1.23 g/cm³ |
| Odor | Characteristic aromatic |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.