China Factory Direct
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| CAS number | 4515-21-3 |
| Product name | N-CARBOBENZOXY-DL-ASPARTIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of β-lactam antibiotics (e.g., amoxicillin, ampicillin) | Participates in the synthesis of peptides or β-lactam side chains via Cbz protection strategy; used to introduce aspartic acid residues in solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Model compound for enzymology studies and chiral resolution experiments | Subjected to enzymatic kinetic resolution leveraging its racemic nature to produce optically active N-Cbz-L- or D-aspartic acid derivatives |
| Peptide Synthesis | Protected aspartic acid monomer for solid-phase or solution-phase peptide synthesis | α-Amino group protected with Cbz (benzyloxycarbonyl); carboxyl group further activated for amide bond formation to suppress side reactions |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 210 nm using a calibrated standard curve. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase with UV detection to determine enantiomeric excess. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content based on stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., ethyl acetate, methanol). |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light in solution to confirm chiral integrity and batch consistency. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient reverse-phase HPLC with UV detection. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Test Item | Specification |
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| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 132-136°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | -10° to +10° (c=1, in 1N HCl) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.