China Factory Direct
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| CAS number | 4519-40-8 |
| Product name | 2,3-Difluoroaniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pesticides | Intermediate for synthesizing fluorinated insecticides and fungicides, e.g., flumetramide and flufenoxuron | Constructs fluorinated aromatic amine structures via diazotization–hydrolysis, halogenation, or direct fluorination |
| Pharmaceuticals | Key aromatic amine building block for antitumor agents (e.g., BRAF inhibitors) and anti-inflammatory drugs | Serves as a starting material in cross-coupling reactions, including Suzuki coupling and Buchwald–Hartwig amination |
| Dyes | Light- and heat-stable auxochrome moiety for high-performance azo and reactive dyes | After diazotization, couples with phenols or amines to introduce the o-difluoroanilino group, enhancing color fastness |
| Materials Science | Building block for fluorinated polyimides, liquid crystal monomers, and organic electroluminescent (OLED) materials | Forms polyimide precursors via acid chloride formation/amidation, or introduces conjugated side chains through iodination followed by Suzuki coupling |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies 2,3-difluoroaniline peak area against a calibration curve using an internal or external standard. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration based on the reaction of iodine with water in a pyridine-methanol solvent system. |
| Residue on Ignition | Gravimetric Analysis | Determines non-volatile inorganic impurities by incinerating sample at 700-800 C and weighing the residual ash. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using an anion-exchange column and conductivity detection. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Measures total heavy metal content after acid digestion by atomic absorption of characteristic wavelengths. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Evaluates yellowness/brownness by comparing sample color to APHA platinum-cobalt standard solutions at 455 nm. |
| Acid Value | Acid-Base Titration | Determines free acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Basic Impurities | Acid-Base Titration | Quantifies volatile basic substances by titration with standardized HCl solution using methyl red indicator. |
| Non-Volatile Residue | Gravimetric Analysis | Measures residue after evaporation of a fixed sample volume under controlled temperature and vacuum. |
| Specific Gravity | Digital Density Meter | Determines density relative to water at 20 C using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measures bending of light through liquid sample at 20 C using sodium D-line (589 nm). |
| Residual Solvents (e.g., toluene, methanol) | Headspace Gas Chromatography (HS-GC) | Quantifies volatile organic solvents by gas-phase equilibrium followed by GC-FID analysis. |
| Test Item | Specification |
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| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.545–1.550 |
| Relative Density (20°C/25°C) | 1.245–1.255 g/cm³ |
| Odor | Characteristic aromatic amine odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.