China Factory Direct
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| CAS number | 452-09-5 |
| Product name | 4-CHLORO-2-FLUOROANISOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antidepressants, antipsychotics, and other central nervous system-active compounds | Introduced into the target molecular scaffold via organic synthesis reactions such as nucleophilic substitution, Suzuki coupling, or reduction |
| Agrochemicals | Used as a synthetic intermediate for agrochemicals, including herbicides and insecticides | Involved in aromatic ring functional group transformations to construct biologically active heterocyclic or aryl ether structures |
| Liquid Crystal Materials | Used as a liquid crystal monomer or intermediate in the production of high-performance liquid crystal display materials | Employed in processes such as Williamson ether synthesis, halogen exchange, or metal-catalyzed coupling to build biphenyl- or pyrimidine-based liquid crystal core structures |
| Fine Chemicals | Used in the synthesis of fragrances, dyes, and other functional chemicals | Serves as an aryl ether building block, participating in selective functionalization reactions within multistep syntheses |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies main component by retention time and peak area comparison against certified reference standard. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and semi-quantifies impurities based on mass spectral fragmentation patterns and retention behavior. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents (e.g., methanol, toluene) via equilibrium vapor phase analysis. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralizes acidic impurities (e.g., residual HCl) using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) | Quantifies trace metals after acid digestion by measuring element-specific atomic emission intensities. |
| Chloride Ion | Ion Chromatography (IC) | Separates and quantifies chloride anions using conductivity detection after ion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue remaining after high-temperature ashing at 700-800 C. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against established visual standards under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light to detect chiral impurities or enantiomeric excess (though compound is achiral, confirms absence of optically active contaminants). |
| Density | Digital Density Meter | Determines mass per unit volume at specified temperature using oscillating U-tube principle. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.530–1.535 |
| Relative Density (20°C/25°C) | 1.240–1.250 g/cm³ |
| Odor | Characteristic aromatic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.