2-Fluoro-5-iodotoluene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 452-68-6 |
| Product name | 2-Fluoro-5-iodotoluene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Fluoro-5-iodotoluene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Fluoro-5-iodotoluene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Fluoro-5-iodotoluene
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in synthesizing fluorinated and iodinated drug molecules, such as precursors to anticancer or central nervous system agents | Introducing aryl structures via palladium-catalyzed coupling reactions (e.g., Suzuki, Heck); or further functionalizing via the iodide group |
| Agrochemical Intermediates | Serving as a key building block for synthesizing fluorinated aromatic agrochemicals (e.g., herbicides, insecticides) | Constructing active molecular scaffolds through nucleophilic substitution or metal-catalyzed cross-coupling at the iodine site |
| Organic Synthesis Reagents | Functioning as a versatile arene synthon for constructing complex fluorinated aromatic frameworks | The iodine atom is replaceable with cyano, amino, alkyl, and other groups; fluorine atoms enhance electronic effects and metabolic stability |
| Materials Science | Employed in synthesizing fluorinated liquid crystal monomers or optoelectronic material precursors | Linking conjugated systems via iodine-involved coupling reactions to tailor optoelectronic properties |
Manufacturing Quality Control of 2-Fluoro-5-iodotoluene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile organic impurities are partitioned into headspace and quantified by GC-FID or GC-MS against calibrated standards. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma–Optical Emission Spectrometry (ICP-OES) | Acid-digested sample is nebulized into high-temperature plasma; elemental emission intensities are measured at characteristic wavelengths. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical generation of iodine reacts stoichiometrically with water; water content is calculated from total charge passed. |
| Residual Iodine (as I₂ or HI) | Redox Titration with Sodium Thiosulfate | Free iodine oxidizes iodide to triiodide, which is titrated with standardized thiosulfate using starch indicator. |
| Acid-Base Impurities (e.g., HI, HOI) | Non-aqueous Acidimetry (Potentiometric Titration) | Titrant (e.g., sodium methoxide) neutralizes acidic impurities in anhydrous solvent; endpoint detected by potential change. |
| Related Substances (e.g., 2-fluorotoluene, 5-iodotoluene, dihalogenated by-products) | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation on reversed-phase C18 column; impurities detected at 220–280 nm and quantified relative to main peak response. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or via automated optical detection as solid transforms to liquid under controlled heating rate. |
| Appearance and Color | Visual Inspection / Hazen (APHA) Color Scale | Comparison of sample solution (in specified solvent, e.g., toluene) against platinum-cobalt standard solutions under controlled lighting. |
| Chloride Content | Ion Chromatography (IC) with Conductivity Detection | Chloride ions separated on anion-exchange column and quantified by conductivity measurement after suppression. |
| Residual Catalyst (e.g., Pd, Cu) | ICP-OES or ICP-MS | After microwave-assisted acid digestion, metal catalyst residues are quantified by elemental emission (ICP-OES) or mass spectrometry (ICP-MS). |
Technical Specifications of 2-Fluoro-5-iodotoluene
| Test Item | Specification |
|---|---|
| Appearance | Colorless to almost colorless clear liquid |
| Purity | >=98.0% (GC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.565–1.575 |
| Relative Density (20°C/25°C) | 1.62–1.64 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Fluoro-5-iodotoluene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Fluoro-5-iodotoluene
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Industrial 2-Fluoro-5-iodotoluene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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