China Factory Direct
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| CAS number | 452-72-2 |
| Product name | 4-Fluoro-2-methylphenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antimicrobial and anti-inflammatory agents | Used in organic synthesis and condensation reactions |
| Agrochemicals | Active ingredient or intermediate in herbicide and insecticide production | Applied in halogenation and esterification reactions |
| Dyes & Pigments | Modifying group in dye synthesis to enhance color fastness or hue properties | Employed in coupling and sulfonation reactions |
| Electronic Materials | Synthesized into liquid crystal materials or semiconductor chemicals | Utilized in purification and vapor deposition processes |
| Research Reagents | Model compound for fluorination or methylation studies | Prepared via laboratory-scale synthesis |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Separation of the sample using a reversed-phase chromatographic column, with quantification of the main component peak area via a UV detector (e.g., 254 nm or 270 nm). Quantification is performed using a standard reference substance, offering excellent reproducibility and high sensitivity. |
| Impurity Analysis | HPLC or GC-MS | HPLC is used for non-volatile impurities; GC-MS is suitable for identifying volatile organic impurities. Unknown impurities are identified by comparing retention times and mass spectra, assessing whether the impurity profile complies with pharmacopeial or corporate standards. |
| Water Content | Karl Fischer Titration | Utilizes an electrochemical titration principle to accurately measure trace amounts of water in samples. Suitable for hydroxyl-containing compounds, avoiding sample decomposition due to high temperatures. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | The sample is placed in a sealed headspace vial and heated; volatile solvents enter the gas phase and are detected by GC-FID or GC-MS. Complies with ICH Q3C guidelines, offering high sensitivity and minimal interference. |
| Melting Point Determination | Capillary Melting Point Apparatus | Observes the temperature range from initial to complete melting of a solid sample to assess purity and crystalline form consistency. Simple to perform and a key physical constant indicator. |
| Appearance and Color | Visual Color Comparison / Colorimeter | Visual observation of color against a white background, or quantification of Lab* values using a colorimeter, ensuring the product exhibits no abnormal discoloration or turbidity. |
| pH Value (Aqueous Solution) | pH Meter Measurement | A solution of defined concentration is prepared and measured using a calibrated pH meter to evaluate whether acidity or alkalinity meets process or stability requirements. |
| Heavy Metal Residues | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After sample digestion, total levels of elements such as lead, cadmium, mercury, and arsenic are determined. ICP-MS offers higher sensitivity for trace analysis; AAS is cost-effective and practical. |
| Fluorine Content Verification | Ionic Chromatography (IC) or Fluoride Ion-Selective Electrode | Fluoride ions are released via combustion or hydrolysis, then quantified using ionic chromatography or a fluoride ion-selective electrode to confirm that the fluorine content in the molecule matches the theoretical value. |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Comprehensive analysis using 1H-NMR, 13C-NMR, FT-IR, and MS data, comparing with reference spectra to confirm molecular structure and integrity of functional groups, used for raw material identification. |
| Test Item | Specification |
|---|---|
| Appearance | Light yellow to brown powder or lumps |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 34.0–37.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.