China Factory Direct
|
|
| CAS number | 45234-13-7 |
| Product name | BOC-CIT-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Protecting reagent for citrulline residues in peptide synthesis | Used as an α-amino protecting group for L-citrulline in solid-phase peptide synthesis (SPPS); the Boc group is selectively removed under acidic conditions (e.g., TFA) to enable controlled coupling |
| Biochemical Research | Preparation of structurally defined citrullinated peptide probes or reference standards | Employed in solution-phase peptide synthesis or fragment condensation to introduce site-specific citrulline modifications, supporting studies of protein arginine deiminase (PAD) activity |
| Diagnostics Reagent Development | Synthesis of antigens for anti-citrullinated protein antibody (ACPA) detection | Conjugated to carrier proteins (e.g., KLH, BSA) to prepare synthetic antigens for in vitro diagnostic kits targeting autoimmune diseases such as rheumatoid arthritis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of enantiomers on a chiral stationary phase; L-isomer content determined by relative peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine water via stoichiometric reaction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents. |
| Heavy Metals | ICP-OES | Multi-element quantification of metal impurities after acid digestion, based on atomic emission intensities. |
| Residual Chloride | Ion Chromatography | Separation and quantification of chloride anions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities using gradient reversed-phase HPLC. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum to determine volatile content. |
| pH of Solution | Potentiometric pH Measurement | Hydrogen ion activity measured using calibrated glass electrode in aqueous suspension or solution. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine size distribution of solid particles in suspension. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms after filtration, membrane transfer, and incubation on nutrient agar. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 172-176°C |
| Optical Rotation | -9.5 to -8.3° (c=1, in 1N HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.