China Factory Direct
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| CAS number | 453565-90-7 |
| Product name | 3-Bromo-5-(trifluoromethoxy)Benzoicacid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediate for synthesizing active pharmaceutical ingredients (APIs) or bioactive molecules | Used in organic synthesis and coupling reactions |
| Agrochemicals | Key intermediate for synthesizing agrochemicals (e.g., herbicides, insecticides) | Applied in halogenation, etherification, and carboxylic acid derivatization |
| Materials Science | Monomer or modifier for preparing fluorinated polymers or specialty polymers | Used in polymerization and functionalization |
| Electronic Chemicals | Synthetic precursor for liquid crystal materials or electron-transport materials | Applied in fine organic synthesis and purification processes |
| Research Reagents | Organic building block or analytical standard | Prepared via laboratory-scale synthesis and chromatographic separation |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., isomers, dehalogenated, hydrolyzed, or oxidation products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-ppt detection limits and compliance with ICH Q3D. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Acid Value | Acid-Base Titration (NaOH, phenolphthalein) | Neutralization of carboxylic acid groups with standardized sodium hydroxide solution; endpoint detected potentiometrically or by indicator. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (e.g., 1–2 °C/min) per USP <741>. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Measurement of non-volatile inorganic residue after high-temperature incineration (~700–800 °C) followed by weighing. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions (e.g., from incomplete bromination or hydrolysis) using anion-exchange column and suppressed conductivity detection. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity; absence of rotation confirms achirality (expected for this compound). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (by LC-MS) |
| Melting Point | 148–152°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 235–245 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.