China Factory Direct
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| CAS number | 4543-58-2 |
| Product name | Benzenesulfonamide, 2,4,6-trimethyl- (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Used as a herbicide intermediate for synthesizing triazolosulfonamide herbicides (e.g., metsulfuron-methyl, chlorsulfuron) | Condensation with isocyanates or amines under basic conditions to form the sulfonylurea linkage |
| Pharmaceuticals | Served as a synthetic intermediate for preparing sulfonamide-containing active pharmaceutical ingredients, including antidiabetic and antineoplastic agents | Conversion to sulfonyl chloride using thionyl chloride, followed by coupling with amines; or direct participation in multistep organic syntheses such as cyclization and substitution |
| Materials Science | Employed as a polymeric modifier and functional monomer to enhance thermal stability and hydrophobicity of polyurethanes, epoxy resins, and related materials | Incorporated into polymer backbones or side chains as a capping agent or comonomer, strengthening intermolecular interactions via sulfonamide linkages |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) against calibrated standards. |
| Moisture Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine water content by stoichiometric reaction with water. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using capillary tube method per USP <741>, reporting onset and clear point. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion, measuring metals (e.g., Pb, Cd, As, Hg) against regulatory thresholds (ICH Q3D). |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified via external calibration. |
| Sulfate Impurity | Turbidimetric Method | Reaction with barium chloride under acidic conditions to form BaSO4 precipitate; absorbance measured at 420 nm. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C to remove organic matter; residue weight expressed as % of original sample. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH electrode measurement of saturated aqueous suspension (1:10 w/v) after equilibration per USP <791>. |
| Bulk Density | Tap Density Analyzer | Mass per unit volume after standardized tapping; reported as g/mL for flow and handling assessment. |
| Particle Size Distribution | Laser Diffraction | Analysis of dispersed dry powder using Mie theory to determine D10, D50, D90 values per ISO 13320. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 124.0–128.0°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.