China Factory Direct
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| CAS number | 454703-20-9 |
| Product name | 1-BOC-3-METHYLAMINOAZETIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a synthetic intermediate for preparing nitrogen-containing heterocyclic drug molecules, including antiviral, antitumor, and central nervous system-active compounds | Used as a BOC-protected azetidine derivative in multistep organic synthesis, participating in nucleophilic substitution, reductive amination, or coupling reactions |
| Agrochemicals | Potential structural building block for novel pesticides or plant growth regulators | Applied as a nitrogen-containing heterocyclic synthon, with functional group transformations enabling incorporation into target molecular frameworks |
| Fine Chemicals | Employed in synthesizing high-value specialty chemicals or functional material precursors | Further derivatized after deprotection (e.g., BOC removal using TFA) to construct complex molecular architectures |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and detection of impurities (e.g., des-Boc, N-oxide, dimer) via gradient HPLC with diode-array detection for spectral confirmation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., THF, DMF, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content based on the stoichiometric reaction of iodine with water in anhydrous pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni, Pd) after acid digestion, achieving sub-pptr detection limits. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride ions using an anion-exchange column and suppressed conductivity detection. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Residual Palladium | ICP-OES | Quantification of residual Pd catalyst post-hydrogenation using inductively coupled plasma optical emission spectrometry after microwave-assisted digestion. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using Mie scattering theory with automated dispersion. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Direct measurement using calibrated pH electrode in aqueous suspension to assess protonation state and salt formation tendency. |
| Test Item | Specification |
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| Appearance | Colorless liquid |
| Purity | >=99.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.3% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | +12.0° to +16.0° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.