China Factory Direct
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| CAS number | 4548-45-2 |
| Product name | 2-Chloro-5-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeElectronic GradeMaterial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibiotic and antiviral drug intermediates | Nitration, chlorination |
| Pesticides | Key raw material for herbicide and insecticide production | Catalytic hydrogenation, condensation |
| Dyes | Preparation of azo dye and nitro dye precursors | Diazotization, coupling |
| Electronic Chemicals | Synthesis of liquid crystal materials and photoresists | Purification, photochemical reaction |
| Research Reagents | Organic synthesis intermediates or analytical standards | Chromatographic separation, crystallization purification |
| Test Item | Common Test Method | Method Overview |
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| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/buffered salt as mobile phase. The UV detector (e.g., 254 nm or 320 nm) quantifies the main component, and purity is calculated using external standard or area normalization method. |
| Related Substances (Impurities) | HPLC with Gradient Elution | Optimized gradient program separates the main peak from potential impurities (e.g., unreacted starting materials, by-products, degradation products). Impurity limits are set (e.g., individual impurity ≤0.5%, total impurities ≤1.0%). |
| Water Content | Karl Fischer Titration | Quantitative reaction between sample moisture and Karl Fischer reagent. The endpoint is determined by potentiometric titration to accurately measure trace water content (typically required ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Headspace or direct injection, separation on capillary column, FID detector for quantification of common organic solvents (e.g., toluene, dichloromethane, ethanol), in compliance with ICH Q3C limits. |
| Melting Point | Capillary Melting Point Apparatus | A small amount of dried sample is packed into a melting point tube. The temperature range from initial melting to complete melting is observed according to pharmacopoeial methods (literature value approximately 79–82°C) to assess crystalline purity. |
| Appearance | Visual Comparison | Observe color (should be pale yellow to yellow crystalline powder), odor, and presence of foreign matter or caking, in accordance with internal company specifications. |
| Loss on Drying | Weight Loss upon Drying (at 105°C to constant weight) | Sample is weighed in a pre-weighed and pre-dried dish, dried at 105°C until constant weight is achieved. The percentage weight loss is calculated (typically ≤0.5%) to estimate volatile content. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Sample is acid-digested, followed by determination of elemental residues such as lead, cadmium, mercury, and arsenic, in compliance with pharmacopoeial standards or ICH Q3D guidelines for elemental impurities. |
| pH (Solution) | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1% w/v), calibrate pH meter, and measure pH to evaluate acidity/basicity and its impact on stability (usually near neutral). |
| Test Item | Specification |
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| Appearance | White to light yellow solid |
| Purity | ≥98.0% |
| Water | ≤0.5% |
| Melting point | 105~110°C |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.