China Factory Direct
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| CAS number | 455-86-7 |
| Product name | 3,4-Difluorobenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key aromatic carboxylic acid intermediate in coupling and amidation reactions to construct fluorinated benzamide compounds |
| Agrochemicals | Synthesis of high-efficiency fungicides and herbicides | Applied in esterification, acid chloride formation, or condensation reactions to incorporate the fluorobenzoic acid structural unit, enhancing compound lipophilicity and biological activity |
| Materials Science | Synthesis of high-performance polymer monomers | Used as a fluorinated aromatic dicarboxylic acid derivative in copolymerization to produce heat-resistant and chemically resistant polyimide or polyester materials |
| Organic Synthesis | General intermediate for constructing fluorinated aromatic frameworks | Applied in metal-catalyzed coupling (e.g., Suzuki, Buchwald–Hartwig), reduction, or substitution reactions to derive functional molecules such as fluorinated anilines and fluorinated phenyl ethers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Related Substances | HPLC with UV detection | Separation and quantification of structurally related impurities (e.g., mono-fluoro isomers, benzoic acid, residual solvents) using gradient elution and UV detection. |
| Residual Solvents (e.g., methanol, acetone, toluene) | Gas Chromatography (GC) with FID or HS-GC | Volatile organic solvents are separated by capillary GC and detected via flame ionization; headspace sampling minimizes matrix interference. |
| Heavy Metals (as Pb) | ICP-MS or AAS after acid digestion | Total heavy metal content determined by atomic absorption or mass spectrometric detection following microwave-assisted nitric acid/hydrogen peroxide digestion. |
| Chloride Content | Ion Chromatography (IC) or potentiometric titration with AgNO₃ | Quantification of chloride ions via separation on anion-exchange column with conductivity detection, or by argentometric titration using silver nitrate. |
| Moisture Content | Karl Fischer Titration (coulometric mode) | Electrochemical determination of water content based on the stoichiometric reaction of iodine with water in a pyridine/methanol solvent system. |
| Melting Point | Capillary melting point apparatus | Thermal transition temperature measured by observing the solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Appearance & Color | Visual inspection against standard solutions (e.g., APHA/Pt-Co scale) | Subjective assessment of physical state and color intensity compared to standardized platinum-cobalt reference solutions. |
| Residue on Ignition | Gravimetric analysis after high-temperature ashing | Non-volatile inorganic residue quantified by weight difference before and after ignition at 700–800 °C per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 126–130 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.