China Factory Direct
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| CAS number | 455-87-8 |
| Product name | 4-AMINO-3-FLUOROBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antitumor drug intermediates | Used as a key intermediate to construct fluorinated aromatic amine structures in active pharmaceutical ingredients; participates in coupling or amidation reactions |
| Pharmaceuticals | Antiviral drug development | Used to synthesize biologically active fluorinated benzoic acid derivatives; amino and carboxyl groups are modified to incorporate the compound into the drug molecule scaffold |
| Pesticides | Insecticide/herbicide intermediates | Serves as a building block in the synthesis of fluorinated aromatic compounds; employed in multi-step organic syntheses to prepare novel pesticide active ingredients |
| Fine chemicals | Liquid crystal material synthesis | Used to prepare high-performance liquid crystal monomers; its rigid aromatic ring and polar functional groups enable tuning of phase transition temperature and dielectric anisotropy |
| Research institutions | Organic synthesis reagent | Acts as a fluorinated, multifunctional aromatic compound for exploratory research in laboratories, including development of new reactions and functional materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., isomers, dehalogenated or oxidized by-products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identifies and quantifies residual solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based reagent stoichiometry. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, As, Ni) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after separation on an anion-exchange column. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion at 700-800 C, expressed as percentage of sample mass. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity based on sharpness and agreement with literature value. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measures mass loss upon heating under controlled conditions to quantify volatile components and residual moisture. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in suspension using angular scattering pattern of laser light. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral integrity and absence of racemization. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-brown solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.