China Factory Direct
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| CAS number | 4559-96-0 |
| Product name | 4'-BROMO-4-CHLOROBUTYROPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a precursor in the synthesis of active pharmaceutical ingredients (APIs), including antidepressants and antipsychotics | Employed as an aryl ketone building block in organic synthesis steps such as Grignard reactions, reductive aminations, or Suzuki couplings |
| Agrochemicals | Used as an intermediate in the synthesis of specific herbicides or insecticides | Applied as a key building block in heterocycle construction or aromatic ring functionalization |
| Organic Synthesis Research | Used to construct complex aromatic ketone compounds or functional material molecules | Utilized to introduce bromo/chloro functional groups—via nucleophilic substitution or metal-catalyzed cross-coupling—to modulate molecular properties |
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase column (e.g., C18) with methanol/water or acetonitrile/water as the mobile phase, and a UV detector (254 nm). It effectively separates the main component from impurities and quantitatively calculates purity. It is one of the most commonly used methods for quality control. |
| Structure Confirmation | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the molecular weight and fragmentation information from mass spectrometry to confirm the compound's molecular formula and structure, and identify potential isomers or degradation products. |
| Molecular Weight Determination | Electrospray Ionization Mass Spectrometry (ESI-MS) | Determines the molecular weight accurately by obtaining quasi-molecular ion peaks ([M+H]⁺ or [M−H]⁻) through soft ionization techniques, assisting in structural confirmation. |
| Residual Solvent Detection | Gas Chromatography (GC) | Uses a capillary column (e.g., DB-5 or similar stationary phase) with a thermal conductivity detector (TCD) or flame ionization detector (FID) to detect residual organic solvents (e.g., ethanol, acetone, dichloromethane) from the synthesis process, complying with ICH Q3A standards. |
| Chlorine Content Detection | X-ray Fluorescence Spectroscopy (XRF) | A non-destructive and rapid method to detect chlorine content in samples, suitable for preliminary screening and batch-to-batch comparison, but needs to be combined with other methods for precise quantification. |
| Bromine Content Detection | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | High-sensitivity detection of bromine content in samples, used to verify the accuracy of bromine substitution positions and whether the content matches theoretical values. |
| Melting Point Determination | Microscopic Melting Point Method | Determines the melting point range by observing the sample's melting behavior during heating, used to initially assess the substance's purity and consistency. |
| Infrared Spectral Analysis (IR) | Fourier Transform Infrared Spectroscopy (FTIR) | Confirms molecular structure by characteristic functional group absorption peaks (e.g., carbonyl ν(C=O) ~1680 cm⁻¹, C-Br, C-Cl stretching vibrations), used for qualitative comparison with standard spectra. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR / ¹³C NMR | Provides detailed molecular structural information, including hydrogen environments, carbon framework structures, and substitution patterns. It is the gold standard for structural confirmation, especially useful for identifying complex impurities. |
| Test Item | Specification |
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| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48–52°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.