2-Chloro-4'-fluoroacetophenone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 456-04-2 |
| Product name | 2-Chloro-4'-fluoroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4'-fluoroacetophenone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4'-fluoroacetophenone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4'-fluoroacetophenone
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antidepressants and antipsychotics | Used to construct drug molecule scaffolds containing a 4'-fluorophenyl moiety |
| Pharmaceuticals | Used in the synthesis of fluoxetine and related pharmaceuticals | Serves as a key starting material or intermediate in fluoxetine synthesis |
| Agrochemicals | Intermediate in the synthesis of fluorinated pesticides | Applied to introduce specific fluorinated acetophenone structures to enhance biological activity or stability |
| Chemicals/Materials | Organic synthesis reagent | Used as an acylating agent in Friedel-Crafts acylation reactions or as a building block in other organic syntheses |
Manufacturing Quality Control of 2-Chloro-4'-fluoroacetophenone
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and gradient elution with UV absorbance at 254 nm. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile solvent residues are equilibrated in headspace vial, injected into GC, and quantified via external calibration. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities using standardized sodium hydroxide solution with phenolphthalein endpoint detection. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Sample digested in acid matrix; elemental emission intensities measured at characteristic wavelengths for heavy metal quantification. |
| Chloride Ion | Ion Chromatography (IC) with conductivity detection | Anion separation on ion-exchange column followed by quantitative detection of chloride via suppressed conductivity. |
| Melting Point | Capillary Melting Point Determination | Thermal transition observed visually or automatically as solid-to-liquid phase change under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria in a white background under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Sample ignited at 700-800 C; residue weight determined after cooling in desiccator to assess inorganic ash content. |
| Bulk Density | USP <616> Tap Density Method | Mass per unit volume measured after mechanical tapping of a known mass in a calibrated cylinder to assess powder flow properties. |
Technical Specifications of 2-Chloro-4'-fluoroacetophenone
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65.0 - 69.0 °C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4'-fluoroacetophenone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4'-fluoroacetophenone
Safety Information of 2-Chloro-4'-fluoroacetophenone
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-4'-fluoroacetophenone
Industrial 2-Chloro-4'-fluoroacetophenone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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