2-Chloro-4-fluorobenzyl bromide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 45767-66-6 |
| Product name | 2-Chloro-4-fluorobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-fluorobenzyl bromide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-fluorobenzyl bromide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-fluorobenzyl bromide
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used to construct fluorinated benzyl side chains in the synthesis of antitumor agents (e.g., EGFR inhibitors) and antimicrobial agents | Undergoes nucleophilic substitution with amines in inert solvents or metal-catalyzed coupling to introduce the target moiety into the molecule |
| Agrochemical Intermediates | Used to synthesize fluorinated benzoic acid–based herbicides and insecticides (e.g., analogues of flonicamid) | Converted to corresponding carboxylic acid derivatives via cyanation, hydrolysis, or oxidation, followed by amidation or esterification |
| Materials Science | Serves as a fluorohalogenated benzyl structural unit in liquid crystal monomers or organic optoelectronic materials | Participates in Suzuki or Heck coupling reactions to build fluorinated conjugated frameworks for OLED or liquid crystal display material synthesis |
Manufacturing Quality Control of 2-Chloro-4-fluorobenzyl bromide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Related Substances | High Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related impurities using a reversed-phase C18 column and gradient elution. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) with FID | Volatile organic solvents are vaporized in sealed vials and quantified by GC-FID using calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water in the sample. |
| Acidity (as HBr) | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., residual HBr) using phenolphthalein indicator or potentiometric endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element trace metal quantification after acid digestion and matrix-matched calibration. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Anion separation on an ion-exchange column followed by quantitative detection via suppressed conductivity. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Mass difference measured before and after high-temperature ashing to determine non-volatile inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or optically as solid-to-liquid phase change under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral compounds in solution at specified concentration and path length. |
| Bulk Density | ASTM D1895 Method A (Tapped Density Tester) | Mass per unit volume determined after mechanical tapping of a known mass in a calibrated cylinder. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Analysis of scattered laser light intensity patterns to calculate size distribution based on Mie theory. |
Technical Specifications of 2-Chloro-4-fluorobenzyl bromide
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-fluorobenzyl bromide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-fluorobenzyl bromide
Safety Information of 2-Chloro-4-fluorobenzyl bromide
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2-Chloro-4-fluorobenzyl bromide
Industrial 2-Chloro-4-fluorobenzyl bromide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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