China Factory Direct
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| CAS number | 458-04-8 |
| Product name | 3-FLUOROPHENYLACETYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical & Agrochemical | Agrochemical Intermediate | Serves as a key synthetic building block for synthesizing fluorinated agrochemicals (e.g., insecticides, herbicides), leveraging the fluorine atom’s properties to enhance biological activity and metabolic stability. |
| Pharmaceutical & Agrochemical | Pharmaceutical Intermediate | Used in synthesizing diverse drug molecules, commonly applied in developing non-steroidal anti-inflammatory drugs or other fluorinated aromatic pharmaceuticals; incorporation of the 3-fluorophenacetyl group optimizes pharmacokinetic properties. |
| Organic Synthesis | Acylation Reagent | Leverages the high reactivity of the acid chloride moiety to introduce the 3-fluorophenacetyl group in Friedel–Crafts acylation or esterification reactions, enabling construction of complex organic molecular frameworks. |
| R&D | Laboratory Reagent | Employed as a starting material or derivatization reagent for synthesizing specific fluorinated compounds in new drug discovery and methodology development, supporting exploration of novel synthetic routes. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard under optimized chromatographic conditions. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based solvent. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of acidic impurities using standardized sodium hydroxide solution and phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Chloride Impurities | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Quantification of total heavy metals by atomization in flame and measurement of characteristic absorption at specific wavelength. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard reference under controlled lighting. |
| Density | Digital Density Meter | Determination of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Measurement of light bending angle at air-sample interface to infer purity and composition. |
| Boiling Point | Distillation Method (ASTM D1078) | Determination of temperature at which vapor pressure equals atmospheric pressure during controlled distillation. |
| Non-Volatile Residue | Evaporation Gravimetry | Weighing residue remaining after evaporation of a fixed sample volume under controlled heating and vacuum. |
| Organic Impurities (Related Substances) | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of structurally related compounds using reversed-phase column and UV absorbance at 220 nm. |
| Test Item | Specification |
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| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.532–1.536 |
| Relative Density (20°C/25°C) | 1.240–1.250 g/cm³ |
| Odor | Pungent, acrid odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.