China Factory Direct
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| CAS number | 459-03-0 |
| Product name | (4-Fluorophenyl)acetone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of the antidepressant fluoxetine | Used to produce fluoxetine via reductive amination with methylamine, followed by reduction with NaBH₄ |
| Pharmaceutical Intermediates | Structural building block for selective serotonin reuptake inhibitor (SSRI) drugs | Serves as a fluorinated arylpropanone scaffold in multistep organic syntheses, including cyclization and substitution reactions |
| Pesticide R&D | Potential fluorinated pesticide active molecule building block | Applied in laboratory research to design novel fluorinated insecticidal or herbicidal lead compounds |
| Organic Synthesis | Standard building block for fluorinated aryl ketone compounds | Commonly employed in functional group transformations such as Grignard reactions, Wittig reactions, α-halogenation, and enolization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantifies 4-fluorophenyl acetone by retention time and peak area comparison against a certified reference standard. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and semi-quantifies impurities based on mass spectral fragmentation patterns and retention behavior. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents (e.g., acetone, toluene) via equilibrium vapor phase analysis. |
| Water Content | Karl Fischer Titration (Coulometric) | Determines trace water by electrochemical titration using iodine generated in situ proportional to water content. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Measures acidic impurities by neutralization with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Color | Visual Comparison Against APHA Scale | Evaluates sample color intensity by matching against platinum-cobalt standard solutions under controlled lighting. |
| Density | Digital Density Meter (Oscillating U-tube) | Determines density from the resonant frequency shift of a vibrating U-shaped tube filled with sample. |
| Refractive Index | Digital Refractometer | Measures refractive index based on critical angle of total internal reflection at the prism-sample interface. |
| Residue on Ignition | Gravimetric Analysis after High-Temperature Ashing | Quantifies non-volatile inorganic residue remaining after combustion at 700-800 C in a muffle furnace. |
| Heavy Metals (as Pb) | Atomic Absorption Spectroscopy (AAS) | Detects total heavy metals by atomization and measurement of absorbance at characteristic wavelengths for lead. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Separates and quantifies chloride ions via conductivity detection (IC) or silver nitrate titration with endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.535–1.545 |
| Relative Density (20°C/25°C) | 1.100–1.120 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.