China Factory Direct
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| CAS number | 459-46-1 |
| Product name | 4-Fluorobenzyl bromide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a synthetic intermediate in the preparation of fluorinated drug molecules, such as antidepressants and antihistamines | Organic synthesis steps including nucleophilic substitution, Suzuki coupling, and Grignard reactions |
| Agrochemicals | Used to synthesize fluorinated active ingredients for agrochemicals, such as herbicides or insecticides | Synthesis processes including halogen exchange, aromatic ring substitution, and metal-catalyzed coupling |
| Materials Science | Used to prepare fluorinated liquid crystal monomers or functional polymeric materials | Introduction of structural units into polymerization reactions, including aromatic electrophilic/nucleophilic substitution |
| Fine Chemicals | Used as fluorinated aromatic building blocks for custom synthesis of specialty chemicals | Participation as a benzylic fluorine or bromine source in multi-step organic syntheses to construct complex molecular frameworks |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance | Visual Inspection | Observe the color, physical state, and clarity of the sample. The pure substance is typically a colorless to pale yellow liquid without suspended particles. |
| Content Assay | Gas Chromatography (GC) | Utilize a capillary column (e.g., DB-5) with a flame ionization detector (FID); qualitative analysis is performed based on retention time, and quantitative analysis is carried out via peak area normalization or external standard method to determine the main component content. |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (approximately 220–254 nm) and gradient elution to detect organic impurities and degradation products. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm structural correctness by analyzing the chemical shifts and coupling constants of hydrogen and fluorine atoms using ¹H-NMR and ¹⁹F-NMR. |
| Bromine Content Determination | Ionic Chromatography (IC) or Titration | IC can measure free bromide ions; argentometric titration (e.g., Fajans or Volhard method) can be used to determine total bromine content to evaluate the degree of substitution. |
| Moisutre Content | Karl Fischer Titration | Quantitatively determine water content in the sample using an electrochemical reaction, suitable for detecting low moisture levels (ppm range). |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, detect organic solvents that may remain from the manufacturing process (e.g., toluene, ethanol, dichloromethane). |
| Acid Value / Hydrogen Bromide Content | Acid-Base Titration | Titrate with standardized NaOH solution to determine the content of free HBr or other acidic impurities, reflecting stability and purity. |
| Test Item | Specification |
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| Appearance | Faint yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Relative Density (20°C/25°C) | 1.530–1.550 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.