Dapagliflozin Tetraacetate Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 461432-25-7 |
| Product name | Dapagliflozin Tetraacetate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for Dapagliflozin Tetraacetate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Dapagliflozin Tetraacetate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Dapagliflozin Tetraacetate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of sodium-glucose co-transporter 2 (SGLT2) inhibitors (e.g., dapagliflozin) for diabetes treatment | Multi-step organic synthesis intermediate used to construct the C-aryl glucoside structural scaffold |
Manufacturing Quality Control of Dapagliflozin Tetraacetate
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) | Compare the sample's infrared absorption spectrum with that of a reference standard or standard spectrum to confirm the presence of characteristic functional groups (e.g., ester, aromatic rings, C–Cl, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze the chemical shifts, coupling constants, and integration area of hydrogen atoms in the compound to verify structural features and stereochemistry. | |
| Mass Spectrometry (MS, e.g., ESI-MS or HRMS) | Determine the molecular ion peak and fragment ions to confirm molecular weight and elemental composition, assisting in structure confirmation. | |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC-UV) | Use a reversed-phase C18 column with acetonitrile/water or methanol/water as mobile phase for gradient elution, and quantify the main component content using a UV detector (e.g., 220–254 nm). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC-DAD or HPLC-UV) | Use chromatographic conditions similar to those for content determination but possibly more sensitive or with higher resolution to detect and quantify process impurities and degradation products. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Use headspace injection or direct injection to detect organic solvents (e.g., dichloromethane, ethanol, ethyl acetate) that may remain from synthesis or purification processes. |
| Moisture | Karl Fischer Titration | Determine the moisture content using volumetric or coulometric methods to ensure compliance with loss on drying or moisture limits. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Determine the total loss of volatile substances (including water and low-boiling impurities) by constant weight at a specified temperature (e.g., 105°C). |
| Melting Point | Melting Point Apparatus | Determine the melting point range of the sample, used as a physical constant for preliminary identification and purity assessment. |
| Optical Purity/Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column to separate enantiomers and evaluate the purity of the target stereoisomer (e.g., 2R,3R,4R,5S,6S). |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect residual harmful metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia or ICH Q3D requirements. |
Technical Specifications of Dapagliflozin Tetraacetate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in chloroform) |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of Dapagliflozin Tetraacetate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Dapagliflozin Tetraacetate
Packaging of Dapagliflozin Tetraacetate
Industrial Dapagliflozin Tetraacetate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply