2-amino-3-cyano-5-methylthiophene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4623-55-6 |
| Product name | 2-amino-3-cyano-5-methylthiophene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-amino-3-cyano-5-methylthiophene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-amino-3-cyano-5-methylthiophene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-amino-3-cyano-5-methylthiophene
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate for synthesizing biologically active thiophene-based compounds, including anti-inflammatory, antimicrobial, and antitumor candidates | Multi-component condensation (e.g., Gewald reaction) to construct the thiophene ring scaffold, followed by functional group transformations to install the target structure |
| Pesticides | Used as an agrochemical intermediate in the synthesis of novel insecticides or herbicides | Nucleophilic substitution or coupling reactions to assemble thiophene-containing bioactive molecules |
| Dyes & Pigments | Used as an organic synthetic intermediate for preparing specialty dyes | Cyclization or coupling reactions to form conjugated chromophores |
| Materials Science | Used as a precursor for synthesizing optoelectronic functional materials (e.g., organic semiconductors, fluorescent probes) | Suzuki coupling, Knoevenagel condensation, and related reactions to build π-conjugated systems |
Manufacturing Quality Control of 2-amino-3-cyano-5-methylthiophene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, toluene, DMF) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with SO2 and base. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification after acid digestion; detection based on mass-to-charge ratio of elemental isotopes. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; quantifies chloride relative to calibration curve. |
| Sulfate Impurity | Ion Chromatography | Same principle as chloride; sulfate eluted and detected via conductivity after suppression. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measurement after high-temperature ashing (700-800 C); residue weight reflects inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or optically as solid-to-liquid phase change; indicates crystallinity and purity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers; used to confirm enantiomeric identity and batch consistency. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to determine volume-based particle size distribution in dry or dispersed state. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after standardized mechanical tapping; reflects powder flow and handling characteristics. |
Technical Specifications of 2-amino-3-cyano-5-methylthiophene
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 78–82°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-amino-3-cyano-5-methylthiophene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-amino-3-cyano-5-methylthiophene
Safety Information of 2-amino-3-cyano-5-methylthiophene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-amino-3-cyano-5-methylthiophene
Industrial 2-amino-3-cyano-5-methylthiophene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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