3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4651-67-6 |
| Product name | 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate in the synthesis of obeticholic acid | Serves as a key precursor in the preparation of obeticholic acid via reduction, iodination, and deiodination steps |
| Pharmaceutical Chemicals | Intermediate in the synthesis of chenodeoxycholic acid (CDCA) and its derivatives | Applied in the preparation of bile acid–based pharmaceuticals through selective carbonyl reduction or structural modification |
| Biochemistry | Steroid metabolism research | Used as a specific metabolite or substrate in enzymatic studies of bile acid metabolic pathways |
| Organic Synthesis | Starting material for steroid skeleton modification | Employed in derivatization reactions leveraging reactive functional groups (hydroxyl and carbonyl) on rings A and C |
Manufacturing Quality Control of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Compare the infrared absorption spectrum of the sample with that of a reference standard to confirm consistency of functional group structures. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H-NMR and ¹³C-NMR to analyze hydrogen and carbon signals in the molecular structure, verifying the accuracy of the compound's structure. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Employ a reversed-phase C18 column with a UV detector (typically at 200–210 nm or set according to the maximum absorption wavelength), using an external standard method for quantifying the main component. |
| Ultraviolet-Visible Spectrophotometry (UV-Vis) | Quantify based on absorbance intensity at a specific wavelength; suitable for rapid determination of high-purity samples. | |
| Purity Test | High-Performance Liquid Chromatography (HPLC) | Evaluate purity of the main peak using area normalization or impurity correction methods, detecting related substances or degradation products. |
| Related Substances (Impurity Analysis) | HPLC / UPLC | Use gradient elution to separate and detect synthesis intermediates, isomers, oxidation or hydrolysis impurities, typically identified by relative retention times. |
| Water Content | Karl Fischer Titration | Accurately determine both free and bound water content in samples; applicable for quality control of active pharmaceutical ingredients (APIs). |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents potentially remaining from manufacturing processes (e.g., methanol, ethanol, acetone, dichloromethane), in compliance with ICH guidelines. |
| Polymorphic Form Analysis | X-Ray Powder Diffraction (XRPD) | Identify different crystalline forms or amorphous states, ensuring physical property consistency between batches. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Analyze melting points, phase transition temperatures, and thermal decomposition behavior to assess thermal stability and crystallinity. |
| Particle Size Distribution | Laser Particle Size Analysis (LSA) | Measure particle size distribution, which influences dissolution properties and formulation processes, especially important for raw material control in solid dosage forms. |
Technical Specifications of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 172–176 °C |
| Optical Rotation | -31.0 to -27.0 ° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
Safety Information of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID
Industrial 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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