Z-ASP-OME Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4668-42-2 |
| Product name | Z-ASP-OME |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-ASP-OME
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-ASP-OME Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-ASP-OME
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a protecting group in the synthesis of antiviral agents (e.g., HIV protease inhibitors) and peptide-based drugs | Applied as a temporary side-chain carboxyl protecting group for aspartic acid in solid-phase or solution-phase peptide synthesis; the benzyloxycarbonyl (Cbz) group is removed via hydrogenolysis, while the methyl ester group undergoes selective hydrolysis or aminolysis |
| Organic Synthesis | Serves as a chiral building block in asymmetric synthesis reactions | Used to prepare N-deprotected or C-functionalized aspartic acid derivatives via palladium-catalyzed debenzylation, basic hydrolysis, or transesterification |
| Biochemical Research | Enables selective modification and protection of aspartic acid residues within peptide sequences | Employed in Fmoc-based solid-phase peptide synthesis strategies, in combination with other protected forms such as Fmoc-Asp(OtBu)-OH, to achieve orthogonal deprotection control |
Manufacturing Quality Control of Z-ASP-OME
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibration standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Digestion followed by inductively coupled plasma optical emission spectroscopy to quantify metals (e.g., Pb, Cd, Ni, Fe) against multi-element calibration curves. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with conductivity detection and external calibration. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C after sulfuric acid treatment; residue weighed to determine inorganic non-volatile impurities. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating purity and identity via comparison to reference material. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated pH electrode and buffer references. |
| Particle Size Distribution | Laser Diffraction | Analysis of dispersed sample in liquid medium using laser diffraction to determine volume-based particle size distribution. |
| Microbial Limits | Membrane Filtration | Filtration of solution through membrane, followed by incubation on selective agar media to enumerate aerobic microorganisms and detect absence of specified pathogens. |
Technical Specifications of Z-ASP-OME
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128~132°C |
| Optical Rotation | -18.0~-15.0° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-ASP-OME
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-ASP-OME
Packaging of Z-ASP-OME
Industrial Z-ASP-OME Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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