Betulinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 472-15-1 |
| Product name | Betulinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Betulinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Betulinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Betulinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Lead compound for development of antitumor, anti-inflammatory, and antiviral drugs | Used as a semi-synthetic starting material; derivatives are prepared via structural modifications (e.g., esterification, amidation, oxidation) for in vitro and animal model pharmacological evaluation |
| Cosmetics | Skin conditioning agent and antioxidant | Incorporated into anti-aging creams and serums at typical concentrations of 0.01–0.1%; exerts efficacy by inhibiting MMP-1 and activating the Nrf2 pathway |
| Natural Products Chemistry | Biomarker and reference standard for quality control of plant-derived materials | Applied as a certified reference standard for quantitative analysis of triterpenoid constituents in birch bark extracts using HPLC-DAD or LC-MS |
| Agriculture | Plant-derived pesticide candidate (research stage) | Evaluating inhibitory activity against Botrytis cinerea and aphids under laboratory conditions via foliar spray or root treatment |
Manufacturing Quality Control of Betulinic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies white birch acid content using reversed-phase chromatography with UV detection at 205 nm. |
| Related Substances | HPLC-DAD | Identifies and quantifies structurally similar impurities by retention time and spectral matching. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) using flame ionization detection. |
| Heavy Metals | ICP-OES | Determines total elemental metals (Pb, Cd, As, Hg, Cr) via inductively coupled plasma optical emission spectroscopy. |
| Water Content | Karl Fischer Titration | Measures trace water by volumetric or coulometric titration with iodine-based reagent. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid groups by titration with standardized KOH solution in ethanol. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary method. |
| Loss on Drying | Gravimetric Method | Determines volatile matter by weight loss after drying under controlled temperature and vacuum. |
| Residue on Ignition | Sulfated Ash Method | Quantifies inorganic residue after high-temperature combustion and sulfuric acid treatment. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by angular rotation of plane-polarized light in solution. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or dispersed particle size profile using Mie scattering theory. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens via filtration and culture-based enumeration. |
Technical Specifications of Betulinic acid
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 286–290 °C |
| Optical Rotation | +7.0 to +8.5 ° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Betulinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Betulinic acid
Packaging of Betulinic acid
Industrial Betulinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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