Betulin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 473-98-3 |
| Product name | Betulin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Betulin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Betulin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Betulin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Research on anti-inflammatory, antiviral, and antitumor active pharmaceutical ingredients; used in developing candidate drugs for hepatitis, cancer, and metabolic disorders | Used as a lead compound for structural modification to synthesize derivatives with improved bioavailability and pharmacological efficacy |
| Cosmetics | Skin anti-aging, skin-lightening, and barrier function repair; incorporated into premium skincare products | Purified after extraction from birch bark and formulated into emulsions, serums, and other dosage forms |
| Food | Natural food additive (in certain regions); research on functional food ingredients | Extracted and refined from natural plant sources, added within regulatory limits |
| Research | Reference standard or control substance for bioactivity studies; tool for investigating cellular signaling pathway modulation mechanisms | High-purity crystallization or chromatographic purification for in vitro or in vivo experiments |
| Agriculture | Potential active ingredient in botanical pesticides or plant growth regulators | Laboratory-scale evaluation of inhibitory effects against pathogens or pests |
Manufacturing Quality Control of Betulin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies white birch alcohol content using reversed-phase HPLC with UV detection at 205 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Identifies and quantifies structurally similar impurities (e.g., betulinic acid, lupeol) via HPLC coupled with diode-array detection and spectral comparison. |
| Residual Solvents | GC-FID | Detects and quantifies residual organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection against calibrated standards. |
| Heavy Metals | ICP-MS | Measures trace levels of toxic elements (Pb, Cd, As, Hg) by inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring mass loss after drying under controlled temperature and vacuum conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines the temperature range over which the solid transitions to liquid using capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures the angle of rotation of plane-polarized light induced by chiral molecules in solution, indicating enantiomeric purity. |
| Residue on Ignition | Sulfated Ash Test | Quantifies inorganic residue after high-temperature incineration of sample with sulfuric acid pretreatment. |
| Water Content | Karl Fischer Titration | Determines trace water by volumetric or coulometric titration using iodine-based reagent reacting stoichiometrically with water. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using Mie scattering theory and laser diffraction analysis. |
| Microbial Limits | Membrane Filtration | Assesses total aerobic microbial count and absence of specified pathogens (E. coli, Salmonella) via filtration, culture, and colony enumeration. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per USP <791>. |
Technical Specifications of Betulin
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 245–249 °C |
| Optical Rotation | +19.5 to +20.5 ° (c=1, in chloroform) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Betulin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Betulin
Packaging of Betulin
Industrial Betulin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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