China Factory Direct
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| CAS number | 47375-34-8 |
| Product name | Boc-L-Tyr(tBu)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of peptide drug intermediates | Deprotection via Boc protecting group removal |
| Chemicals | Amino-protecting reagent in organic synthesis | Boc protection of amino acids |
| Materials Science | Synthesis of functional materials | As a precursor for tyrosine-containing structural materials |
| Biotechnology | Key raw material in peptide synthesis | Used in solid-phase or solution-phase peptide synthesis |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample under natural light or standard illumination for color and physical state (typically white to off-white crystalline powder), and assess compliance with specified criteria. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Obtain infrared absorption spectrum of the sample and compare with reference spectrum; HPLC: Under specific chromatographic conditions, the retention time of the main peak in the sample should match that of the reference standard. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with appropriate acetonitrile-water or methanol-water mobile phase; detect using UV detector (typically 210–220 nm); calculate content by external standard method. Generally requires ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Apply gradient or isocratic elution program to separate and detect potential process impurities and degradation products. Individual impurities typically ≤0.5%, total impurities ≤1.0%. |
| Specific Rotation | Polarimeter Method | Prepare a solution at a specified concentration (e.g., 1% w/v, in ethanol or water), measure optical rotation at a defined wavelength (usually sodium D line, 589 nm) and temperature (e.g., 20°C or 25°C), then calculate specific rotation. Should fall within the literature range (e.g., -7° to -9°). |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant-Temperature Drying at Atmospheric Pressure | Dry the sample at 105°C until constant weight; determine the percentage of mass loss. Typically requires ≤0.5%. |
| Residue on Ignition | High-Temperature Ashing Method | Char the sample, then ignite at 700–800°C in a muffle furnace; weigh the residual inorganic matter. Usually requires ≤0.1%. |
| Water Content | Karl Fischer Titration | Determine water content using either volumetric or coulometric Karl Fischer titration. Typically requires ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Based on ICH Q3C guidelines, use headspace GC to detect organic solvents (e.g., dichloromethane, methanol, ethyl acetate) potentially remaining from synthesis, ensuring compliance with specified limits. |
| pH Value (if applicable) | pH Meter Method | Prepare an aqueous solution at a specified concentration (e.g., 1%), measure pH using a calibrated pH meter. Typically neutral or slightly acidic. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148~152°C |
| Optical Rotation | -17.0 to -13.0° (c=1, in 1M HCl) |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.