Glycocholic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 475-31-0 |
| Product name | Glycocholic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Glycocholic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Glycocholic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Glycocholic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of biliary disorders, including cholecystitis and gallstones, as a choleretic agent | Used directly as an active pharmaceutical ingredient (API) in drug formulation manufacturing |
| Pharmaceuticals | Biochemical reagent for in vitro diagnostics and scientific research, e.g., enzyme activity or cellular function assays | Purified and used as a reference standard or analytical reagent |
| Food | Food additive in dietary supplements and foods for special medical purposes to support fat digestion | Blended with other ingredients to produce capsule or powder formulations |
| Research | Surfactant or membrane stabilizer in cell culture and biological experiments | Dissolved in buffer solutions or culture media to prepare working concentration solutions |
Manufacturing Quality Control of Glycocholic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Glycocholic Acid Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and a UV detector (typically 200–210 nm), with gradient elution using methanol-buffer solutions to separate and quantify glycocholic acid from other bile acids. This method offers high sensitivity and good reproducibility. |
| Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) | Combines the high separation power of liquid chromatography with the high selectivity and sensitivity of mass spectrometry, suitable for accurate quantification of glycocholic acid in complex matrices. Commonly used for biological samples or quality control of high-purity formulations. | |
| Purity Test | Thin-Layer Chromatography (TLC) | Uses silica gel plates developed with an appropriate mobile phase (e.g., ethyl acetate-methanol-water-ammonia), followed by visualization to observe the main spot and impurity spots. Provides a preliminary assessment of glycocholic acid purity; simple to perform but with relatively low sensitivity. |
| HPLC Method (Impurity Analysis) | Uses HPLC to detect related substances (such as other conjugated bile acids or free bile acids) in glycocholic acid samples. Impurity levels are calculated based on peak areas, ensuring compliance with pharmacopoeial purity requirements. | |
| Identification | Infrared Spectroscopy (IR) | The sample is mixed with potassium bromide and pressed into a pellet. The infrared absorption spectrum is measured and compared with that of a reference standard or reference spectrum to confirm consistency of functional groups, used for qualitative identification. |
| Nuclear Magnetic Resonance Spectroscopy (NMR) | Uses ¹H-NMR or ¹³C-NMR to analyze characteristic peaks of molecular structure, confirming the chemical structure of glycocholic acid. Mainly used for structural verification of reference standards or newly prepared samples. | |
| Water Content Determination | Karl Fischer Titration | Determines water content in the sample based on electrochemical titration principles. Suitable for moisture control in glycocholic acid active pharmaceutical ingredients (APIs) to ensure stability. |
| Residual Solvent Test | Gas Chromatography (GC) | Uses a capillary column and FID detector to test for residual organic solvents (e.g., methanol, ethanol, acetone) possibly remaining from manufacturing processes, ensuring compliance with ICH permissible limits. |
Technical Specifications of Glycocholic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 192-196°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Optical Rotation | -35° to -41° (c=1, in 0.1N NaOH) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Glycocholic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Glycocholic acid
Packaging of Glycocholic acid
Industrial Glycocholic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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