China Factory Direct
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| CAS number | 475-83-2 |
| Product name | NUCIFERINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Development of anti-obesity and lipid-lowering drugs | Used as a natural bioactive ingredient in drug development targeting lipid metabolism regulation |
| Pharmaceuticals | Neuroprotective effect research | Applied in in vitro and animal model studies of neurodegenerative diseases such as Alzheimer’s disease |
| Cosmetics | Anti-aging and skin-firming | Incorporated into anti-wrinkle creams and firming serums to leverage its antioxidant properties |
| Food | Natural functional food additive | Used as a botanical extract in weight-management teas and dietary supplements |
| Research | Alkaloid compound research | Employed as a reference standard or control substance in chromatographic analysis and bioactivity screening |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~285 nm. |
| Related Substances | HPLC-UV or HPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., nuciferine isomers, oxidation products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Heavy Metals (Total) | ICP-OES | Multi-element quantification of toxic metals (Pb, Cd, As, Hg, Cr) after acid digestion, based on atomic emission intensity at element-specific wavelengths. |
| Loss on Drying (LOD) | Gravimetric (105 °C, 2 h) | Mass loss measured after drying under standardized temperature and time conditions, reflecting volatile content including water and residual solvents. |
| Residue on Ignition (Sulfated Ash) | Gravimetric (500–600 °C) | Mass of inorganic residue remaining after charring and sulfated ashing, indicating non-volatile inorganic impurities. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution at 20 °C using sodium D-line (589 nm), confirming chiral integrity and identity. |
| pH (1% aqueous suspension) | Potentiometric pH measurement | Determination of surface acidity/basicity via glass electrode in a standardized aqueous suspension, reflecting protonation state and salt content. |
| Microbial Limits | Membrane Filtration / TSA/SDA | Quantitative estimation of aerobic bacteria, yeasts, and molds using selective culture media and incubation per pharmacopoeial guidelines (e.g., USP <61>). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 210-215°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15° to -25° (c=1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.