China Factory Direct
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| CAS number | 477600-69-4 |
| Product name | (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an intermediate in the synthesis of bioactive molecules or drug candidates | Organic synthesis, chiral separation, purification |
| Academic Research | Employed in chemical and pharmacological studies to investigate biological activity or as a tool compound | Laboratory-scale synthesis, activity screening |
| Drug Development | Serves as a building block for preparing potential neuroactive or receptor-targeting drugs | Multistep synthesis, structural modification, in vitro testing |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification by retention time matching and/or spiked reference standards. |
| Chiral Purity | (S,S)-Enantiomeric Excess | Chiral HPLC with chiral stationary phase to separate (3S,4S) from (3R,4R), (3S,4R), and (3R,4S) diastereomers; calculated from peak areas. |
| Residual Solvents | GC-FID | Quantifies common solvents (e.g., methanol, ethyl acetate, toluene) using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration using iodine-based redox reaction in anhydrous methanol/pyridine medium. |
| Heavy Metals | ICP-OES | Determines total heavy metal content (Pb, Cd, Hg, As, Ni, Co) after acid digestion by measuring elemental emission intensities at characteristic wavelengths. |
| Residual Palladium | ICP-MS | Quantifies residual Pd catalyst (ppb level) after microwave-assisted digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by ignition at 700-800 C followed by precise weighing of residue after cooling in desiccator. |
| Particle Size Distribution | Laser Diffraction | Measures dry powder particle size distribution using Mie scattering theory applied to laser light diffraction patterns. |
| Bulk Density | Tap Density Measurement | Determines bulk and tapped density using standardized cylinder and mechanical tapping device per USP <616>. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and absence of specified pathogens (E. coli, S. aureus, P. aeruginosa) via membrane filtration followed by incubation on selective media. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | [α]²⁰D = +15.0° to +17.0° (c=1.0 in methanol) |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/4°C) | 0.98–1.02 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.