Z-ASP-OBZL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 4779-31-1 |
| Product name | Z-ASP-OBZL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-ASP-OBZL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-ASP-OBZL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-ASP-OBZL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a protecting group in the synthesis of antiviral agents (e.g., HIV protease inhibitors) and peptide-based drugs | Applied in solid-phase or solution-phase peptide synthesis as a dual protecting group for the side-chain carboxyl and α-carboxyl groups of aspartic acid; deprotection achieved via hydrogenolysis to remove both benzyloxycarbonyl (Cbz) and benzyl (Bn) groups |
| Peptide Synthesis | Selective protection of the α- and β-carboxyl groups of aspartic acid to enable directional coupling | Amide bond formation conducted using coupling reagents such as DCC/HOBt or DIC/Oxyma; subsequent deprotection performed via Pd/C-catalyzed hydrogenolysis or TFA/Sc(OTf)₃ treatment |
| Biochemical Research | Preparation of structurally defined aspartic acid-modified peptide segments for enzyme substrate specificity studies or protein–protein interaction probes | Introduced as a pre-protected monomer in Fmoc-SPPS strategies to support high-purity, high-yield linear peptide chain assembly |
Manufacturing Quality Control of Z-ASP-OBZL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content via stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and nebulization into inductively coupled plasma. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract using anion-exchange column and suppressed conductivity detection. |
| Residual Benzyl Chloride | GC-MS | Detection and quantification of benzyl chloride via headspace GC coupled with mass spectrometric identification and selected ion monitoring. |
| Optical Rotation | [alpha]D | Measurement of specific rotation using sodium D-line light source in solution; confirms chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant eutectic impurities. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum, reflecting volatile content including residual solvents and moisture. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of a standardized suspension in water or water-isopropanol mixture using calibrated glass electrode to assess acidic/basic degradation products. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution via laser scattering pattern analysis, relevant for filtration and handling consistency. |
Technical Specifications of Z-ASP-OBZL
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | -10.5 to -10.0° (c=1, in DMF) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-ASP-OBZL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-ASP-OBZL
Packaging of Z-ASP-OBZL
Industrial Z-ASP-OBZL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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