(R)-3-N-CBZ-AMINO-PIPERIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 478646-32-1 |
| Product name | (R)-3-N-CBZ-AMINO-PIPERIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-3-N-CBZ-AMINO-PIPERIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-3-N-CBZ-AMINO-PIPERIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-3-N-CBZ-AMINO-PIPERIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing antiviral agents (e.g., HCV NS5A inhibitors) and central nervous system (CNS) drugs | Used in coupling, deprotection, and cyclization reactions following asymmetric synthesis or chiral resolution |
| Pharmaceuticals | Construction of chiral drug molecules containing a piperidine ring | Applied as a key chiral building block to introduce the (R)-configured piperidine structural unit in multistep total synthesis |
Manufacturing Quality Control of (R)-3-N-CBZ-AMINO-PIPERIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Enantiomeric Purity | Chiral HPLC | Measures (R)-enantiomer excess using a chiral stationary phase and UV detection; resolution depends on enantioselective interaction. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., MeOH, EtOAc, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water mass fraction via coulometric or volumetric titration using iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pd, Ni, Fe) by plasma ionization followed by mass spectrometric detection. |
| Residual Palladium | ICP-OES | Measures palladium residue from catalytic hydrogenation using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., deprotected, over-reduced, or diastereomeric forms) by gradient HPLC-UV. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate. |
| Specific Optical Rotation | [a]D Measurement | Measures angle of plane-polarized light rotation in solution at 589 nm to confirm chiral integrity and concentration. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample using Mie scattering theory to determine volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of (R)-3-N-CBZ-AMINO-PIPERIDINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | +24.5° to +26.5° (c=1, in methanol) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-3-N-CBZ-AMINO-PIPERIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-3-N-CBZ-AMINO-PIPERIDINE
Packaging of (R)-3-N-CBZ-AMINO-PIPERIDINE
Industrial (R)-3-N-CBZ-AMINO-PIPERIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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