Indirubin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 479-41-4 |
| Product name | Indirubin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Indirubin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Indirubin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Indirubin
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antitumor agents (e.g., for chronic myeloid leukemia), anti-inflammatory, and antiviral research | Used as an active pharmaceutical ingredient in traditional Chinese medicine compound formulations (e.g., Compound Qingdai Pills) and as a lead compound in modern drug discovery; efficacy is typically evaluated via oral administration or in vitro cell-based assays |
| Research | Reference standard in natural product chemistry and medicinal chemistry; control substance for biological activity screening | Applied in quantitative analysis by HPLC and LC-MS; used to study cellular proliferation inhibition (MTT assay), apoptosis induction, and signaling pathway mechanisms (e.g., STAT3, NF-κB) |
| Dyes (Historical Use) | Oxidation by-product of natural indigo dye; formerly employed for traditional textile dyeing (now largely obsolete) | Co-generated during the fermentation-oxidation process for indigo production from indigo-yielding plants (e.g., Indigofera tinctoria, Polygonum tinctorium); isolated and purified in small quantities for limited historical use; no practical application in modern industrial dyeing |
Manufacturing Quality Control of Indirubin
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at ~290 nm. |
| Related Substances | HPLC-DAD | Separation and detection of structurally similar impurities using gradient HPLC with diode-array detection for spectral confirmation. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., methanol, acetone, DMF) based on retention time and flame ionization response. |
| Heavy Metals (as Pb) | AAS (Flame or Graphite Furnace) | Atomic absorption spectroscopy measures absorbance of ground-state atoms vaporized in flame or graphite furnace; calibrated against lead standards. |
| Loss on Drying (LOD) | Gravimetric (Thermogravimetric) | Mass loss measured after drying at 105 C for 2 hours under controlled atmospheric conditions. |
| Residue on Ignition (Sulfated Ash) | Gravimetric (Sulfated Ash Test) | Inorganic residue mass determined after charring, sulfuric acid treatment, and incineration at 600-700 C. |
| Melting Point | Capillary Melting Point Apparatus | Temperature range at which solid-to-liquid phase transition occurs, observed visually in capillary tube under controlled heating rate. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and wavelength (e.g., Na D line). |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate volume-based particle size distribution in dispersed suspension. |
| pH of Aqueous Suspension | pH Meter | Electrometric measurement of hydrogen ion activity in a defined aqueous suspension (e.g., 1% w/v) using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration / Plate Count | Enumeration of aerobic mesophilic bacteria and fungi via filtration, membrane transfer to selective agar media, and colony counting after incubation. |
Technical Specifications of Indirubin
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 193–197 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Indirubin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Indirubin
Packaging of Indirubin
Industrial Indirubin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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