China Factory Direct
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| CAS number | 481-72-1 |
| Product name | Aloe emodin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Anti-inflammatory | Used in the manufacture of anti-inflammatory drugs to mitigate inflammation by inhibiting the production of inflammatory mediators. |
| Pharmaceuticals | Anticancer | Applied in anticancer drug research and development, based on demonstrated inhibitory effects against certain cancer cell lines. |
| Cosmetics | Antioxidant | Incorporated into skincare formulations to counteract free radical damage and support skin health through its antioxidant properties. |
| Cosmetics | Acne treatment | Formulated into acne treatment products to reduce skin inflammation and erythema. |
| Food industry | Natural colorant | Added to food products as a natural colorant to enhance visual appeal while delivering potential health benefits. |
| Functional foods | Health supplement ingredient | Used as an ingredient in health supplements to support gastrointestinal health, with potential anti-inflammatory and antioxidant activity. |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | A C18 reversed-phase column is used with a mobile phase of methanol-water or acetonitrile-water (with acid to adjust pH) under gradient elution. Detection is performed at 254 nm or 280 nm using a UV detector. Aloe-emodin content is quantified by external or internal standard methods. This method offers high sensitivity and good reproducibility, and is commonly used in pharmacopoeias. |
| Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Aloe-emodin shows characteristic absorption peaks at approximately 225 nm, 257 nm, 290 nm, and 430 nm. Preliminary identification is achieved by comparing the UV spectra of the sample with that of the reference standard. Simple to operate, this method is suitable for rapid screening. |
| Identification and Impurity Testing | Thin-Layer Chromatography (TLC) | Silica gel G plates are used with a developing solvent system such as petroleum ether-ethyl acetate-formic acid. After development, fluorescent spots (appearing yellow or orange) are observed under UV light (365 nm), or visualized by spraying with a coloring reagent (e.g., 10% sulfuric acid in ethanol) followed by heating. This method is suitable for identification and impurity testing. |
| Structural Confirmation | Mass Spectrometry (MS) or Liquid Chromatography-Mass Spectrometry (LC-MS) | The molecular ion peak [M-H]⁻ (m/z ≈ 269) is obtained using an electrospray ionization (ESI) source, and structural confirmation is achieved by analyzing fragment ion patterns. LC-MS enables simultaneous separation and structural identification, making it suitable for trace component analysis in complex matrices. |
| Purity Testing | High-Performance Liquid Chromatography (HPLC) | Basing on the assay method, purity of the aloe-emodin peak is evaluated using peak area normalization or external standard methods for impurities, to assess the levels of related substances (e.g., other anthraquinone components) and ensure compliance with quality standards. |
| Residual Solvent Testing | Gas Chromatography (GC) | If aloe-emodin is obtained via extraction or synthesis, residual organic solvents (e.g., methanol, ethanol, benzene) must be tested. A capillary column with an FID detector is used, following the requirements of the Chinese Pharmacopoeia or ICH guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 222–226°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.