4-ACETYL-3-FLUOROPHENYLBORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 481725-35-3 |
| Product name | 4-ACETYL-3-FLUOROPHENYLBORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-ACETYL-3-FLUOROPHENYLBORONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing fluorinated arylboronic acid-based targeted anticancer drugs (e.g., BTK inhibitors, PARP inhibitors) | Used in Suzuki-Miyaura cross-coupling reactions |
| Materials Science | Used to prepare fluorinated organic light-emitting diode (OLED) hole-transport and electron-transport materials | Palladium-catalyzed C–C bond formation to incorporate fluorinated arylboronic acid structural units |
| Pesticide Development | Structural modification unit for lead compound optimization of novel fluorinated insecticides and herbicides | Boronic acid group-directed regioselective functionalization and coupling of aromatic rings |
Manufacturing Quality Control of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and detection of impurities (e.g., starting materials, de-boronated or hydrolyzed analogs) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., THF, MeOH, EtOAc) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pd, Ni, Fe) after acid digestion, using mass spectrometric detection for ultra-trace sensitivity. |
| Residual Palladium | ICP-OES | Quantification of residual Pd catalyst post-synthesis by inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract to assess salt impurity from synthesis. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating and visual observation of solid-to-liquid phase change. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Loss on Drying | Gravimetric Analysis | Mass loss determination after drying under vacuum at specified temperature/time, indicating volatile and moisture content. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light to confirm chiral purity (if applicable) and absence of racemization. |
| pH of Aqueous Suspension | pH Meter | Determination of acidity/basicity in a defined water/solvent suspension using calibrated pH electrode. |
Technical Specifications of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
Safety Information of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-ACETYL-3-FLUOROPHENYLBORONIC ACID
Industrial 4-ACETYL-3-FLUOROPHENYLBORONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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