China Factory Direct
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| CAS number | 4842-86-8 |
| Product name | Ethyl piperidine-3-carboxylate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antiviral agents (e.g., HCV NS5A inhibitors) and neuroactive compounds | Employed as a chiral building block in coupling reactions, reductive amination, or hydrolysis-cyclization steps |
| Agrochemical R&D | Applied as a structural modification unit for novel insecticides and plant growth regulators | Modified via ester group transformation to introduce heterocyclic side chains, optimizing molecular lipophilicity and target binding affinity |
| Organic Synthesis | Utilized as a nitrogen-containing heterocyclic building block for constructing piperidine-based functional molecules | Processed through selective protection/deprotection, N-alkylation, or C-functionalization for multi-step synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperidine-3-carboxylic acid ethyl ester hydrochloride) | Acid-base titration with NaOH | Quantifies total acid content by neutralizing HCl salt with standardized NaOH using phenolphthalein indicator. |
| Water Content | Karl Fischer titration | Measures water via iodine-sulfur dioxide redox reaction in methanol-based reagent. |
| Residual Solvents (Ethanol, Dichloromethane) | Gas chromatography (GC-FID) | Separates and quantifies volatile solvents using capillary column and flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Detects trace metals by ionizing sample in plasma and measuring mass-to-charge ratios with high sensitivity. |
| Chloride Impurity | Potentiometric titration with AgNO3 | Determines chloride concentration via argentometric titration using silver nitrate and silver electrode. |
| Related Substances | HPLC-UV | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection at 210 nm. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC | Resolves enantiomers on chiral stationary phase and calculates ee from peak area ratio. |
| pH of 5% Aqueous Solution | pH meter measurement | Measures hydrogen ion activity in aqueous suspension using calibrated pH electrode. |
| Melting Point | Capillary melting point apparatus | Determines temperature range at which solid transitions to liquid under controlled heating. |
| Loss on Drying | Gravimetric analysis at 105 C | Measures volatile content by weight loss after drying under specified temperature and time. |
| Appearance (Color and Clarity) | Visual inspection against standard solutions | Compares sample solution color and turbidity to reference standards in matched cuvettes under controlled lighting. |
| Residue on Ignition | Sulfated ash gravimetry | Quantifies non-volatile inorganic residue after high-temperature combustion in sulfuric acid medium. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.