China Factory Direct
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| CAS number | 485-35-8 |
| Product name | CYTISINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing anticancer and neurodegenerative disease therapeutics | Functionalized via multistep organic synthesis leveraging cytisine’s alkaloid structure |
| Biochemical Research | Model natural product for investigating the biological activity mechanisms of alkaloids | Applied in in vitro cell assays and animal models to study its effects on the nervous system |
| Pesticide Development | Structural template for plant-derived insecticidal lead compounds | Structurally optimized and derivatized based on its inherent antimicrobial and insecticidal activities |
| Chemical Reagents | Used as a reference standard or reaction reagent in laboratory research | Applied in qualitative analysis and reactivity testing of alkaloid compounds |
| Test Item | Common Testing Method | Method Overview |
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| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a mobile phase of methanol-buffer solution (e.g., phosphate buffer). Detection is performed using a UV detector (200–220 nm), and quantification of cytisine content is achieved via external or internal standard methods. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Same as above; purity is evaluated by comparing the main peak area to the total impurity peak areas. Commonly used for quality control of raw materials or extracts. |
| Structural Confirmation | Mass Spectrometry (MS) | Electrospray ionization (ESI) or electron ionization (EI) is used to obtain molecular ion peaks and fragment ion information of cytisine. Structure is confirmed by comparison with reference spectra. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H-NMR and ¹³C-NMR are used to analyze the chemical environments of hydrogen and carbon atoms in cytisine, enabling structural identification of high-purity samples. |
| Qualitative Identification | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Scans absorption spectrum in the 200–300 nm range, utilizing characteristic absorption peaks of cytisine (e.g., around 210 nm) for preliminary qualitative identification. |
| Residual Solvent Testing | Gas Chromatography (GC) | Suitable for detecting residual organic solvents (e.g., methanol, ethanol, chloroform) from extraction or synthesis processes, ensuring compliance with pharmacopeial limits for residual solvents. |
| Moisture Content | Karl Fischer Titration | Accurately measures moisture content in samples; essential for raw material quality control to prevent stability issues due to hygroscopicity. |
| Heavy Metals and Impurities | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detects residual heavy metals such as lead, cadmium, arsenic, and mercury to ensure compliance with pharmaceutical safety standards. |
| Related Substances Testing | HPLC or TLC | HPLC separates and detects degradation products or synthetic by-products in cytisine. Thin-layer chromatography (TLC) serves as a simple and rapid screening method for impurities, using visualizing agents (e.g., iodine vapor or sulfuric acid in ethanol) to observe spots. |
| Test Item | Specification |
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| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 148–152°C |
| Optical Rotation | -109 to -115° (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.